LIG4 and APLF

  • Number of citations of the paper that reports this interaction (PMID 17396150)
  • 36
  • Data Source:
  • HPRD (in vitro)

LIG4

APLF

Gene Name ligase IV, DNA, ATP-dependent aprataxin and PNKP like factor
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
Protein-Protein Interactions 103 interactors: ACTG1 AFTPH AGAP4 ALMS1 AMZ2P1 ANAPC10 APLF ASPM ATM ATP6V0D1 ATR B9D1 CAP1 CCDC176 CLU COL1A2 COMMD1 COX1 COX2 COX3 CPNE1 CREBBP CTSK DDX19A DGUOK DPP3 EIF2AK1 EIF3I EIF4A1 EIF4G3 ENO1 ETF1 FAM214A FBLL1 FIP1L1 GAPDH GGH GPANK1 GRHPR GUSBP3 GZMK HMGN1 HNRNPA2B1 IPP KDELR1 KIF3A LAP3 MAP2K2 MCM4 MCRS1 MRPS18C ND1 ND4 ND5 NDUFA13 NDUFB10 NEU1 NHEJ1 NOMO3 NPC2 OGFOD1 OSTM1 OXR1 PA2G4 PALLD PEX10 PGP PHF10 PMS2P1 PPIA PRKDC PSMA6 RBM5 RHBDD2 RPL11 RPS19BP1 RUVBL2 SEMA4G SMC2 SNX3 SOWAHC SRSF2 SYCP3 THOC5 TLE4 TOP1 TP53BP1 TPT1 TRAPPC3 TSFM UBB UBE2L3 UFSP2 UNC119 VKORC1 WARS WBP1L WDR20 XRCC4 ZFAND2A ZNF428 ZSCAN18 ZWINT 9 interactors: APP FBXO25 GMCL1 IRX5 LIG4 PARP1 XRCC1 XRCC4 XRCC5
Entrez ID 3981 200558
HPRD ID 03500 09848
Ensembl ID ENSG00000174405 ENSG00000169621
Uniprot IDs P49917 Q8IW19
PDB IDs 1IK9 2E2W 3II6 3VNN 3W1B 3W1G 3W5O 4HTO 4HTP 2KQB 2KQC 2KQD 2KQE 2KUO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  mechanistically  nhej  overhang  parp1  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
acidic  adp  analogs  ation  binds  chaperone  chaperones  chromatin  collectively  define  eukaryotes  exhibits  h4  histone  histones  homologous  localize  modulates  motif  nap1l  poly  poorly  preferentially  reactions  relaxation  repair  ribose  ribosyl  tetramer 
Tagcloud (Difference) ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  instability  insufficient  joining  ku70  lig3  mechanistically  nhej  overhang  parp1  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
acidic  adp  analogs  ation  binds  chaperone  chaperones  chromatin  collectively  define  eukaryotes  exhibits  h4  histone  histones  localize  modulates  motif  nap1l  poly  poorly  preferentially  reactions  relaxation  repair  ribose  ribosyl  tetramer 
Tagcloud (Intersection) ?
homologous