LIG4 and SMC2

  • Number of citations of the paper that reports this interaction (PMID 12589063)
  • 7
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro, two hybrid)

LIG4

SMC2

Gene Name ligase IV, DNA, ATP-dependent structural maintenance of chromosomes 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
  • Orofacial clefts (interaction) ( 21618603)
Protein-Protein Interactions 103 interactors: ACTG1 AFTPH AGAP4 ALMS1 AMZ2P1 ANAPC10 APLF ASPM ATM ATP6V0D1 ATR B9D1 CAP1 CCDC176 CLU COL1A2 COMMD1 COX1 COX2 COX3 CPNE1 CREBBP CTSK DDX19A DGUOK DPP3 EIF2AK1 EIF3I EIF4A1 EIF4G3 ENO1 ETF1 FAM214A FBLL1 FIP1L1 GAPDH GGH GPANK1 GRHPR GUSBP3 GZMK HMGN1 HNRNPA2B1 IPP KDELR1 KIF3A LAP3 MAP2K2 MCM4 MCRS1 MRPS18C ND1 ND4 ND5 NDUFA13 NDUFB10 NEU1 NHEJ1 NOMO3 NPC2 OGFOD1 OSTM1 OXR1 PA2G4 PALLD PEX10 PGP PHF10 PMS2P1 PPIA PRKDC PSMA6 RBM5 RHBDD2 RPL11 RPS19BP1 RUVBL2 SEMA4G SMC2 SNX3 SOWAHC SRSF2 SYCP3 THOC5 TLE4 TOP1 TP53BP1 TPT1 TRAPPC3 TSFM UBB UBE2L3 UFSP2 UNC119 VKORC1 WARS WBP1L WDR20 XRCC4 ZFAND2A ZNF428 ZSCAN18 ZWINT 8 interactors: ABCC5 DISC1 DNMT3B GULP1 LIG4 NCAPD2 SMC4 TRAF3IP1
Entrez ID 3981 10592
HPRD ID 03500 09277
Ensembl ID ENSG00000174405 ENSG00000136824
Uniprot IDs P49917 A8K984 B3KMB1 B7ZLZ7 O95347 Q05BV1 Q05D74 Q6IPS5 Q7Z2X1
PDB IDs 1IK9 2E2W 3II6 3VNN 3W1B 3W1G 3W5O 4HTO 4HTP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  mechanistically  nhej  overhang  parp1  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
called  complementary  cyclins  dissociated  dnas  ectopic  elucidate  eventually  g2  gst  hec  heptad  hydrolyzes  inhibits  interacts  leucine  mitosis  mitotic  modulate  mss1  nek2  p45  proteasome  proteolysis  pull  repeats  seventh  smc1  telophase 
Tagcloud (Difference) ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  mechanistically  nhej  overhang  parp1  rampant  relies  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
called  complementary  cyclins  dissociated  dnas  ectopic  elucidate  eventually  g2  gst  hec  heptad  hydrolyzes  inhibits  interacts  leucine  mitosis  mitotic  modulate  mss1  nek2  p45  proteasome  proteolysis  pull  seventh  smc1  telophase 
Tagcloud (Intersection) ?
repeats