ATR and UPF1

  • Number of citations of the paper that reports this interaction (PMID 16488880)
  • 55
  • Data Source:
  • BioGRID (enzymatic study)

ATR

UPF1

Gene Name ATR serine/threonine kinase UPF1 regulator of nonsense transcripts homolog (yeast)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 47 interactors: AATF ABL1 AP1B1 AP2A2 ARHGEF1 ATM ATRIP BLM BRCA1 BRCA2 CDKN2C CEP164 CHD4 CHEK1 CHEK2 CLSPN CREB1 DCLRE1C DTL E2F1 E4F1 EEF1E1 EP300 FANCA FANCD2 FLT1 H2AFX KDR LIG4 MCM2 MRE11A MSH2 NBN PA2G4 PIK3CA POLD1 POLN PPP2R2A PTS RAD17 RHEB TP53 TREX1 UPF1 VPRBP XPA XRCC5 31 interactors: ABHD16A ACSS2 ATR CSNK2B DCP1A DCP2 DXO EIF3A EIF3B EIF4A3 EXOSC2 EXOSC4 GNPTG GSPT2 HIRA LSM8 NADSYN1 NDRG1 NDUFB10 PLEKHA5 PLEKHB2 POLR2A RHOXF2 RPRD2 SMG1 SMG5 STAU1 UPF2 UPF3A UPF3B XRN1
Entrez ID 545 5976
HPRD ID 08369 03254
Ensembl ID ENSG00000175054 ENSG00000005007
Uniprot IDs Q13535 Q92900
PDB IDs 2GJK 2GK6 2GK7 2IYK 2WJV 2WJY 2XZO 2XZP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
aav9  adeno  als  amyotrophic  cord  decay  empty  exerts  forelimb  green  helps  implicate  mycupf1  nmd  nonsense  otherwise  paralysis  quadriplegic  recapitulate  reproducible  respective  spinal  tdp  titrated  transactive  twofold  upframeshift  validate  vector 
Tagcloud (Difference) ?
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
aav9  adeno  als  amyotrophic  cord  decay  empty  exerts  forelimb  green  helps  implicate  mycupf1  nmd  nonsense  otherwise  paralysis  quadriplegic  recapitulate  reproducible  respective  spinal  tdp  titrated  transactive  twofold  upframeshift  validate  vector 
Tagcloud (Intersection) ?