RUFY1 and AP3M1

Number of citations of the paper that reports this interaction (PMID 23144738)
1

Data Source:
BioGRID (pull down)

		RUFY1	AP3M1
Gene Name		RUN and FYVE domain containing 1	adaptor-related protein complex 3, mu 1 subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Membrane Intracellular Membrane-bounded Organelle	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Lipid Binding Protein Transporter Activity	Protein Binding Rab GTPase Binding
	Biological Process	Endocytosis Protein Transport Regulation Of Endocytosis	Protein Targeting To Lysosome Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport
Pathways			Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Eating disorders ( 22911880)	Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-Protein Interactions		17 interactors: AP3B2 AP3D1 AP3M1 AP3S1 BMX DIEXF EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TCF3 TXNDC17	8 interactors: AGTRAP AQP4 CRMP1 RSPH14 RUFY1 SIPA1L2 TGOLN2 TRIM9
Entrez ID		80230	26985
HPRD ID		15282	16496
Ensembl ID		ENSG00000176783
Uniprot IDs		A8K7B1 Q96T51	B4DRN6 Q9Y2T2
PDB IDs		2YQM 2YW8
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Intracellular Protein Transport Anterograde Axon Cargo Transport Synaptic Vesicle Transport Axon Cargo Transport Rab Protein Signal Transduction Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Intracellular Transport Vesicle Localization Protein Localization Microtubule-based Transport Establishment Of Organelle Localization Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Signaling Cell Communication Organelle Localization Cellular Localization Ras Protein Signal Transduction Post-Golgi Vesicle-mediated Transport Synaptic Transmission Microtubule-based Movement Cytoplasmic Transport Cell-cell Signaling Endosomal Transport Regulation Of Ras GTPase Activity Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance Small GTPase Mediated Signal Transduction Golgi Vesicle Transport Regulation Of Ras Protein Signal Transduction Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Synaptic Vesicle Membrane Organization Cellular Response To Stimulus Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Regulation Of GTPase Activity Canonical Wnt Signaling Pathway Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Endosome Size Response To Stimulus Membrane Organization Eye Pigment Biosynthetic Process Movement Of Cell Or Subcellular Component	Negative Regulation Of SNARE Complex Assembly Carbon Dioxide Transport Renal Water Absorption Renal Water Transport Angiotensin-activated Signaling Pathway Regulation Of SNARE Complex Assembly Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Vesicle Fusion Hyperosmotic Salinity Response Glycerol Transport Renal Absorption Polyol Transport Regulation Of Vesicle-mediated Transport Cellular Water Homeostasis
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