RUFY1 and RAB14

Number of citations of the paper that reports this interaction (PMID 20534812)
17

Data Source:
BioGRID (two hybrid, pull down)

		RUFY1	RAB14
Gene Name		RUN and FYVE domain containing 1	RAB14, member RAS oncogene family
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Intracellular Lysosome Lysosomal Membrane Early Endosome Late Endosome Rough Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol Plasma Membrane Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Early Endosome Membrane Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Protein Binding Zinc Ion Binding Lipid Binding Protein Transporter Activity	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Endocytosis Protein Transport Regulation Of Endocytosis	Intracellular Protein Transport Golgi To Endosome Transport Fibroblast Growth Factor Receptor Signaling Pathway Embryo Development Vesicle-mediated Transport Endocytic Recycling Rab Protein Signal Transduction Regulation Of Protein Localization Intracellular Transport Membrane Organization Phagolysosome Assembly Involved In Apoptotic Cell Clearance
Pathways			Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		Eating disorders ( 22911880)	Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions		17 interactors: AP3B2 AP3D1 AP3M1 AP3S1 BMX DIEXF EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TCF3 TXNDC17	9 interactors: APP CHM EXOC5 OCRL OPTN RAB11FIP5 RBSN RUFY1 SMURF2
Entrez ID		80230	51552
HPRD ID		15282	06693
Ensembl ID		ENSG00000176783	ENSG00000119396
Uniprot IDs		A8K7B1 Q96T51	P61106
PDB IDs		2YQM 2YW8	1Z0F 4DRZ
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Intracellular Protein Transport Anterograde Axon Cargo Transport Synaptic Vesicle Transport Axon Cargo Transport Rab Protein Signal Transduction Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Intracellular Transport Vesicle Localization Protein Localization Microtubule-based Transport Establishment Of Organelle Localization Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Signaling Cell Communication Organelle Localization Cellular Localization Ras Protein Signal Transduction Post-Golgi Vesicle-mediated Transport Synaptic Transmission Microtubule-based Movement Cytoplasmic Transport Cell-cell Signaling Endosomal Transport Regulation Of Ras GTPase Activity Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance Small GTPase Mediated Signal Transduction Golgi Vesicle Transport Regulation Of Ras Protein Signal Transduction Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Synaptic Vesicle Membrane Organization Cellular Response To Stimulus Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Regulation Of GTPase Activity Canonical Wnt Signaling Pathway Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Endosome Size Response To Stimulus Membrane Organization Eye Pigment Biosynthetic Process Movement Of Cell Or Subcellular Component	Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Exocytosis Protein Localization Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Cellular Localization Secretion By Cell Synaptic Growth At Neuromuscular Junction Intracellular Transport Secretion Collateral Sprouting In Absence Of Injury Negative Regulation Of Receptor Recycling Transport Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Insulin Secretion Involved In Cellular Response To Glucose Stimulus Axon Choice Point Recognition Golgi Ribbon Formation Ubiquitin-dependent SMAD Protein Catabolic Process Membrane Organization Cellular Response To Acidic PH Protein Geranylgeranylation Establishment Of Protein Localization To Membrane Neuron Remodeling Golgi Vesicle Transport Positive Regulation Of Hydrolase Activity
Tagcloud ?			a2 abundantly alveolar annexin bodies details egfp immunoprecipitated indeed interference lamellar localized microarray nevertheless overexpressing phospholipid regulated rescued returned secretion selected silenced silencing surfactant tagged targets thirteen transcriptome validated
Tagcloud (Difference) ?			a2 abundantly alveolar annexin bodies details egfp immunoprecipitated indeed interference lamellar localized microarray nevertheless overexpressing phospholipid regulated rescued returned secretion selected silenced silencing surfactant tagged targets thirteen transcriptome validated
Tagcloud (Intersection) ?