RUFY1 and AP3B2

Number of citations of the paper that reports this interaction (PMID 23144738)
1

Data Source:
BioGRID (pull down)

		RUFY1	AP3B2
Gene Name		RUN and FYVE domain containing 1	adaptor-related protein complex 3, beta 2 subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Membrane Intracellular Membrane-bounded Organelle	Nucleoplasm Cytoplasm Golgi Apparatus AP-3 Adaptor Complex COPI-coated Vesicle Clathrin-coated Vesicle Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Lipid Binding Protein Transporter Activity	Transporter Activity
	Biological Process	Endocytosis Protein Transport Regulation Of Endocytosis	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport
Pathways
Drugs
Diseases
GWAS		Eating disorders ( 22911880)	Lipoprotein-associated phospholipase A2 activity change in response to statin therapy ( 23118302)
Protein-Protein Interactions		17 interactors: AP3B2 AP3D1 AP3M1 AP3S1 BMX DIEXF EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TCF3 TXNDC17	6 interactors: ADAP1 AP3S1 ATM CLTC CSNK1A1 RUFY1
Entrez ID		80230	8120
HPRD ID		15282	03699
Ensembl ID		ENSG00000176783	ENSG00000103723
Uniprot IDs		A8K7B1 Q96T51	B7ZKR7 B7ZKS0 Q13367
PDB IDs		2YQM 2YW8
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Intracellular Protein Transport Anterograde Axon Cargo Transport Synaptic Vesicle Transport Axon Cargo Transport Rab Protein Signal Transduction Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Intracellular Transport Vesicle Localization Protein Localization Microtubule-based Transport Establishment Of Organelle Localization Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Signaling Cell Communication Organelle Localization Cellular Localization Ras Protein Signal Transduction Post-Golgi Vesicle-mediated Transport Synaptic Transmission Microtubule-based Movement Cytoplasmic Transport Cell-cell Signaling Endosomal Transport Regulation Of Ras GTPase Activity Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance Small GTPase Mediated Signal Transduction Golgi Vesicle Transport Regulation Of Ras Protein Signal Transduction Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Synaptic Vesicle Membrane Organization Cellular Response To Stimulus Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Regulation Of GTPase Activity Canonical Wnt Signaling Pathway Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Endosome Size Response To Stimulus Membrane Organization Eye Pigment Biosynthetic Process Movement Of Cell Or Subcellular Component	Vesicle-mediated Transport Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Peptidyl-serine Phosphorylation Endocytosis Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Cellular Component Organization Negative Regulation Of Hyaluronan Biosynthetic Process Pre-B Cell Allelic Exclusion Cell Cycle Process Pre-B Cell Differentiation Histone MRNA Catabolic Process Replicative Senescence Mitotic Nuclear Division Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Immature B Cell Differentiation DNA Damage Induced Protein Phosphorylation Negative Regulation Of Cell Cycle G2/M Phase Transition Cell Cycle Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Transport Lipoprotein Catabolic Process
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