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RUFY1 and BMX
Number of citations of the paper that reports this interaction (PMID
11877430
)
14
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, enzymatic study)
HPRD
(two hybrid, in vivo)
RUFY1
BMX
Gene Name
RUN and FYVE domain containing 1
BMX non-receptor tyrosine kinase
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Early Endosome Membrane
Intracellular Membrane-bounded Organelle
Cytosol
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Ruffle Membrane
Molecular Function
Protein Binding
Zinc Ion Binding
Lipid Binding
Protein Transporter Activity
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Signal Transducer Activity
Receptor Binding
Protein Binding
ATP Binding
Metal Ion Binding
Biological Process
Endocytosis
Protein Transport
Regulation Of Endocytosis
Adaptive Immune Response
Protein Phosphorylation
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cell Adhesion
Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Mesoderm Development
Cell Differentiation
Intracellular Signal Transduction
Peptidyl-tyrosine Autophosphorylation
Regulation Of Cell Proliferation
Innate Immune Response
Protein Autophosphorylation
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Pathways
Apoptotic cleavage of cellular proteins
Programmed Cell Death
Apoptotic execution phase
Drugs
Diseases
GWAS
Eating disorders (
22911880
)
Protein-Protein Interactions
17 interactors:
AP3B2
AP3D1
AP3M1
AP3S1
BMX
DIEXF
EPHA3
GIT2
ITSN2
PIAS2
RAB14
RAB39B
RAB3IP
RAB4A
RAB5A
TCF3
TXNDC17
23 interactors:
APP
BCAR1
BTK
C12orf45
CASP3
CAV1
EGFR
ERBB2
FBXO25
ITK
KDR
PAK1
PTK2
PTPN21
RAP1A
RUFY1
RUFY2
SRC
STAT1
STAT3
STAT5A
TEC
TNFRSF1B
Entrez ID
80230
660
HPRD ID
15282
02111
Ensembl ID
ENSG00000176783
ENSG00000102010
Uniprot IDs
A8K7B1
Q96T51
P51813
PDB IDs
2YQM
2YW8
2EKX
2YS2
3SXR
3SXS
Enriched GO Terms of Interacting Partners
?
Anterograde Synaptic Vesicle Transport
Intracellular Protein Transport
Anterograde Axon Cargo Transport
Synaptic Vesicle Transport
Axon Cargo Transport
Rab Protein Signal Transduction
Cellular Protein Localization
Protein Transport
Vesicle-mediated Transport
Establishment Of Protein Localization
Establishment Of Vesicle Localization
Intracellular Transport
Vesicle Localization
Protein Localization
Microtubule-based Transport
Establishment Of Organelle Localization
Cytoskeleton-dependent Intracellular Transport
Establishment Of Localization In Cell
Signaling
Cell Communication
Organelle Localization
Cellular Localization
Ras Protein Signal Transduction
Post-Golgi Vesicle-mediated Transport
Synaptic Transmission
Microtubule-based Movement
Cytoplasmic Transport
Cell-cell Signaling
Endosomal Transport
Regulation Of Ras GTPase Activity
Transport
Phagolysosome Assembly Involved In Apoptotic Cell Clearance
Small GTPase Mediated Signal Transduction
Golgi Vesicle Transport
Regulation Of Ras Protein Signal Transduction
Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Synaptic Vesicle Membrane Organization
Cellular Response To Stimulus
Regulation Of Small GTPase Mediated Signal Transduction
Microtubule-based Process
Regulation Of GTPase Activity
Canonical Wnt Signaling Pathway
Receptor Internalization Involved In Canonical Wnt Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis
Regulation Of Endosome Size
Response To Stimulus
Membrane Organization
Eye Pigment Biosynthetic Process
Movement Of Cell Or Subcellular Component
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Protein Autophosphorylation
Cell Surface Receptor Signaling Pathway
Immune System Process
Peptidyl-tyrosine Phosphorylation
Peptidyl-tyrosine Autophosphorylation
Regulation Of Cell Proliferation
Intracellular Signal Transduction
Response To Organic Substance
Regulation Of Immune System Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cellular Response To Growth Factor Stimulus
Cellular Response To Organic Substance
Response To Growth Factor
Regulation Of Immune Response
Fc Receptor Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Cellular Response To Organonitrogen Compound
Positive Regulation Of Cellular Metabolic Process
Immune Response-regulating Signaling Pathway
Response To Wounding
Defense Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell Differentiation
Positive Regulation Of Metabolic Process
Response To Stress
Phosphorylation
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Innate Immune Response
Response To Organonitrogen Compound
Cellular Response To Hormone Stimulus
Neurotrophin Signaling Pathway
Wound Healing
Regulation Of Cell Death
Signal Transduction
Peptidyl-amino Acid Modification
Response To Hormone
Response To Peptide Hormone
Immune Response
Protein Phosphorylation
Cell Activation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Cell Activation
Signaling
Response To Peptide
Cell Communication
Growth Hormone Receptor Signaling Pathway
Regulation Of Protein Kinase Activity
Tagcloud
?
additive
androgen
attenuation
btk
chemo
confer
correlates
ctn06
docetaxel
dtx
dual
etk
grades
healing
herein
immortalized
impeded
independence
killing
never
pc3
perception
prostate
raf
sensitizer
tec
vegfr
wound
xenograft
Tagcloud (Difference)
?
additive
androgen
attenuation
btk
chemo
confer
correlates
ctn06
docetaxel
dtx
dual
etk
grades
healing
herein
immortalized
impeded
independence
killing
never
pc3
perception
prostate
raf
sensitizer
tec
vegfr
wound
xenograft
Tagcloud (Intersection)
?