RUFY1 and RAB3IP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RUFY1	RAB3IP
Gene Name		RUN and FYVE domain containing 1	RAB3A interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Membrane Intracellular Membrane-bounded Organelle	Nucleus Centrosome Cytosol Cytoskeleton Lamellipodium Ciliary Basal Body
	Molecular Function	Protein Binding Zinc Ion Binding Lipid Binding Protein Transporter Activity	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Endocytosis Protein Transport Regulation Of Endocytosis	Protein Targeting To Membrane Golgi To Plasma Membrane Transport Organelle Organization Positive Regulation Of Rab GTPase Activity Protein Localization To Organelle Cilium Assembly
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Eating disorders ( 22911880)
Protein-Protein Interactions		17 interactors: AP3B2 AP3D1 AP3M1 AP3S1 BMX DIEXF EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TCF3 TXNDC17	19 interactors: BANP CHCHD3 FAM124A KRT40 MVP NAA10 PLOD3 PPL RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TRAPPC6A ZNF410
Entrez ID		80230	117177
HPRD ID		15282	10565
Ensembl ID		ENSG00000176783	ENSG00000127328
Uniprot IDs		A8K7B1 Q96T51	Q96QF0
PDB IDs		2YQM 2YW8
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Intracellular Protein Transport Anterograde Axon Cargo Transport Synaptic Vesicle Transport Axon Cargo Transport Rab Protein Signal Transduction Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Intracellular Transport Vesicle Localization Protein Localization Microtubule-based Transport Establishment Of Organelle Localization Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Signaling Cell Communication Organelle Localization Cellular Localization Ras Protein Signal Transduction Post-Golgi Vesicle-mediated Transport Synaptic Transmission Microtubule-based Movement Cytoplasmic Transport Cell-cell Signaling Endosomal Transport Regulation Of Ras GTPase Activity Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance Small GTPase Mediated Signal Transduction Golgi Vesicle Transport Regulation Of Ras Protein Signal Transduction Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Synaptic Vesicle Membrane Organization Cellular Response To Stimulus Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Regulation Of GTPase Activity Canonical Wnt Signaling Pathway Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Endosome Size Response To Stimulus Membrane Organization Eye Pigment Biosynthetic Process Movement Of Cell Or Subcellular Component	Synaptic Vesicle Exocytosis Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Neurotransmitter Secretion Synaptic Vesicle Transport Golgi Vesicle Fusion To Target Membrane Protein Secretion Protein Localization Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Ras Protein Signal Transduction Organelle Fusion Protein Transport Establishment Of Protein Localization Establishment Of Organelle Localization Exocytosis Positive Regulation Of Regulated Secretory Pathway Membrane Fusion Organelle Localization Vesicle-mediated Transport Regulation Of Regulated Secretory Pathway Secretion By Cell Vesicle Organization Keratinization Skin Development Regulation Of Cellular Localization Vesicle Fusion Synaptic Transmission Organelle Organization Regulation Of Neuronal Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Small GTPase Mediated Signal Transduction Epidermis Development Secretion Positive Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Secretion N-terminal Peptidyl-glutamic Acid Acetylation N-terminal Peptidyl-serine Acetylation Positive Regulation Of Transport Cellular Protein Localization Keratinocyte Differentiation Constitutive Secretory Pathway Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane
Tagcloud ?			11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses
Tagcloud (Difference) ?			11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses
Tagcloud (Intersection) ?