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MAP3K3 and YWHAQ
Number of citations of the paper that reports this interaction (PubMedID
14743216
)
0
Data Source:
HPRD
(in vitro)
MAP3K3
YWHAQ
Description
mitogen-activated protein kinase kinase kinase 3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Metal Ion Binding
Protein Serine Kinase Activity
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Transmembrane Transporter Binding
14-3-3 Protein Binding
Biological Process
MAPK Cascade
Blood Vessel Development
Intracellular Signal Transduction
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Protein Autophosphorylation
Positive Regulation Of P38MAPK Cascade
Protein Targeting
Signal Transduction
Small GTPase-mediated Signal Transduction
Intracellular Protein Localization
Substantia Nigra Development
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of DNA-templated Transcription
Pathways
Interleukin-1 signaling
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Drugs
Fostamatinib
Phenethyl Isothiocyanate
Diseases
GWAS
Adult body size (
32376654
)
Appendicular lean mass (
33097823
)
Height (
18391951
21998595
22021425
25429064
28552196
)
Hip circumference adjusted for BMI (
34021172
)
Waist circumference adjusted for body mass index (
34021172
)
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Interacting Genes
44 interacting genes:
BIRC2
BRCA1
CDC37
COPS5
EGFR
GAB1
GLRX3
GTF2I
HSP90AA1
HSP90AB1
HSPA2
IKBKB
LATS1
MAP2K3
MAP2K4
MAP2K5
MAP2K7
MAP3K5
MAP3K7
MARK2
MBP
NEDD4
NEDD4L
NFKBIA
PFDN2
PRKACA
RCAN1
RIPK1
SMURF1
SPAG9
TOM1L1
TRAF6
TRAF7
VWF
WNK1
XIAP
YAP1
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
ZBTB16
216 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
AR
ARHGAP10
ARHGEF16
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDKN1A
CDKN1B
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC7
HNRNPC
HNRNPH1
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
ITCH
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LYST
MAGOH
MAP3K3
MAP3K5
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NEDD4L
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PANK1
PDCD6
PDE3A
PDE3B
PDE4B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C3
PIK3CB
PKM
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RIPK2
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SKIC8
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR77
WTAP
WWC2
WWP1
YAP1
YWHAG
ZC3H13
ZHX2
Entrez ID
4215
10971
HPRD ID
03965
00886
Ensembl ID
ENSG00000198909
ENSG00000134308
Uniprot IDs
J3KRN4
J3QRB6
Q96HN9
Q99759
P27348
PDB IDs
2C60
2JRH
2O2V
2PPH
4Y5O
4YL6
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
Enriched GO Terms of Interacting Partners
?
Intracellular Signal Transduction
Intracellular Signaling Cassette
MAPK Cascade
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Protein Metabolic Process
Cytosol
Positive Regulation Of Metabolic Process
Canonical NF-kappaB Signal Transduction
Regulation Of Primary Metabolic Process
Signal Transduction
Identical Protein Binding
Negative Regulation Of Signal Transduction
Cytoplasm
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Protein Modification Process
Positive Regulation Of Macromolecule Metabolic Process
Cellular Response To Stress
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Developmental Process
Protein Serine Kinase Activity
Positive Regulation Of Protein Metabolic Process
Protein Polyubiquitination
Regulation Of Macromolecule Metabolic Process
Transferase Activity
Protein Domain Specific Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein-containing Complex
Positive Regulation Of Biosynthetic Process
Phosphoserine Residue Binding
Protein Modification Process
Response To Tumor Necrosis Factor
Protein Kinase Binding
Regulation Of Metabolic Process
Kinase Activity
Negative Regulation Of Intracellular Signal Transduction
Enzyme Binding
Fc-epsilon Receptor Signaling Pathway
Ubiquitin Protein Ligase Binding
Regulation Of Apoptotic Process
Stress-activated Protein Kinase Signaling Cascade
Cellular Response To Tumor Necrosis Factor
Cellular Response To Cytokine Stimulus
Cytosol
Cytoplasm
Regulation Of Signaling
Regulation Of Cell Communication
Intracellular Signal Transduction
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Protein Metabolic Process
ATP Binding
Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Metabolic Process
Nucleus
Cadherin Binding
Kinase Activity
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Nucleotide Binding
Regulation Of Biological Quality
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cortex
Cellular Response To Oxygen-containing Compound
Response To Stress
Protein-containing Complex
Glucose Catabolic Process
Organelle Organization
Positive Regulation Of Multicellular Organismal Process
Macromolecule Metabolic Process
ADP Metabolic Process
RNA Binding
Cellular Response To Lipid
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Extracellular Exosome
Regulation Of Organelle Organization
Positive Regulation Of Cell Population Proliferation
Glycolytic Process
Cellular Response To Hormone Stimulus
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Tagcloud (Difference)
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Tagcloud (Intersection)
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