Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
PNPLA2 and UBE2R2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
PNPLA2
UBE2R2
Gene Name
patatin-like phospholipase domain containing 2
ubiquitin-conjugating enzyme E2R 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Lipid Particle
Cytosol
Plasma Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Cytoplasm
Molecular Function
Triglyceride Lipase Activity
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Phospholipid Metabolic Process
Negative Regulation Of Sequestering Of Triglyceride
Positive Regulation Of Triglyceride Catabolic Process
Triglyceride Catabolic Process
Lipid Storage
Lipid Particle Organization
Acylglycerol Acyl-chain Remodeling
Small Molecule Metabolic Process
Glycerophospholipid Biosynthetic Process
Protein Monoubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Pathways
Metabolism of lipids and lipoproteins
Acyl chain remodeling of DAG and TAG
Phospholipid metabolism
Glycerophospholipid biosynthesis
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
ABHD5
ARFGEF2
CYTH2
FAF2
GBF1
MARK3
PHYHIP
SERPINF1
SMAD9
UBE2R2
17 interactors:
APPBP2
ARHGDIA
ARIH2
BTRC
CBLC
CSNK2A1
CSNK2A2
DTX3L
DZIP3
FBXW5
INF2
MEOX1
PNPLA2
RBX1
RNF113B
UBA1
UBC
Entrez ID
57104
54926
HPRD ID
11443
15602
Ensembl ID
ENSG00000177666
ENSG00000107341
Uniprot IDs
Q96AD5
Q712K3
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of ARF Protein Signal Transduction
Regulation Of Catalytic Activity
Positive Regulation Of Hydrolase Activity
Post-Golgi Vesicle-mediated Transport
Cellular Response To Cobalt Ion
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Catalytic Activity
Negative Regulation Of Sequestering Of Triglyceride
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Triglyceride Catabolic Process
Regulation Of GTPase Activity
Mullerian Duct Regression
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Receptor Recycling
Response To Cobalt Ion
Golgi Vesicle Transport
Short-term Memory
COPI-coated Vesicle Budding
Positive Regulation Of Lipoprotein Lipase Activity
COPI Coating Of Golgi Vesicle
Positive Regulation Of Metabolic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Modification Process
Cellular Macromolecule Catabolic Process
Protein Polyubiquitination
Catabolic Process
Cellular Protein Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Proteolysis
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Regulation Of Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein Metabolic Process
Mitotic Cell Cycle Checkpoint
Regulation Of Proteasomal Protein Catabolic Process
Mitotic Spindle Checkpoint
Protein Monoubiquitination
Negative Regulation Of Chromosome Segregation
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Cycle Process
Regulation Of Cell Cycle Phase Transition
Cell Cycle Checkpoint
Spindle Checkpoint
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Mitotic Metaphase/anaphase Transition
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Wnt Signaling Pathway
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Wnt Signaling Pathway
Rhythmic Process
Tagcloud
?
abhd5
agpat2
anomaly
atgl
cgi
ctgm
dgat1
diverge
enteropathy
gk
glycerol
gpd1
hsl
ichthyosis
inborn
jordan
lipe
lipodystrophy
loosing
lpin1
lpin2
majeed
nlsd
perilipin
pseudohypertriglyceridemia
rhabdomyolysis
steatosis
tgs
vacuolated
Tagcloud (Difference)
?
abhd5
agpat2
anomaly
atgl
cgi
ctgm
dgat1
diverge
enteropathy
gk
glycerol
gpd1
hsl
ichthyosis
inborn
jordan
lipe
lipodystrophy
loosing
lpin1
lpin2
majeed
nlsd
perilipin
pseudohypertriglyceridemia
rhabdomyolysis
steatosis
tgs
vacuolated
Tagcloud (Intersection)
?