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PNPLA2 and CYTH2
Number of citations of the paper that reports this interaction (PMID
21789191
)
8
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
PNPLA2
CYTH2
Gene Name
patatin-like phospholipase domain containing 2
cytohesin 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Lipid Particle
Cytosol
Plasma Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Cytoplasm
Trans-Golgi Network
Plasma Membrane
Membrane
Molecular Function
Triglyceride Lipase Activity
ARF Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Lipid Binding
Inositol 1,4,5 Trisphosphate Binding
Biological Process
Phospholipid Metabolic Process
Negative Regulation Of Sequestering Of Triglyceride
Positive Regulation Of Triglyceride Catabolic Process
Triglyceride Catabolic Process
Lipid Storage
Lipid Particle Organization
Acylglycerol Acyl-chain Remodeling
Small Molecule Metabolic Process
Glycerophospholipid Biosynthetic Process
Endocytosis
Vesicle-mediated Transport
Actin Cytoskeleton Organization
Regulation Of Cell Adhesion
Regulation Of ARF Protein Signal Transduction
Positive Regulation Of GTPase Activity
Pathways
Metabolism of lipids and lipoproteins
Acyl chain remodeling of DAG and TAG
Phospholipid metabolism
Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
ABHD5
ARFGEF2
CYTH2
FAF2
GBF1
MARK3
PHYHIP
SERPINF1
SMAD9
UBE2R2
21 interactors:
ADORA2A
APC
ARF1
ARF6
ARFGAP1
ARRB1
ARRB2
ATP6V0A2
CCDC120
CUX1
CYTIP
DYT10
GNAQ
IPCEF1
ITGB2
MAPK6
PNPLA2
PRKCA
PRKCB
PRKCG
TRIM23
Entrez ID
57104
9266
HPRD ID
11443
03925
Ensembl ID
ENSG00000177666
ENSG00000105443
Uniprot IDs
Q96AD5
Q99418
PDB IDs
1PBV
1R8M
1R8Q
1R8S
1S9D
Enriched GO Terms of Interacting Partners
?
Regulation Of ARF Protein Signal Transduction
Regulation Of Catalytic Activity
Positive Regulation Of Hydrolase Activity
Post-Golgi Vesicle-mediated Transport
Cellular Response To Cobalt Ion
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Catalytic Activity
Negative Regulation Of Sequestering Of Triglyceride
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Triglyceride Catabolic Process
Regulation Of GTPase Activity
Mullerian Duct Regression
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Receptor Recycling
Response To Cobalt Ion
Golgi Vesicle Transport
Short-term Memory
COPI-coated Vesicle Budding
Positive Regulation Of Lipoprotein Lipase Activity
COPI Coating Of Golgi Vesicle
Positive Regulation Of Metabolic Process
Blood Coagulation
Hemostasis
Platelet Activation
Regulation Of Body Fluid Levels
Wound Healing
Cell Activation
Response To Wounding
Signal Transduction
Apoptotic Process
Programmed Cell Death
Signaling
Histone H3-T6 Phosphorylation
Cell Death
Death
Cell Communication
Positive Regulation Of Metabolic Process
Regulation Of Receptor Internalization
Cellular Response To Stimulus
Regulation Of Phosphorus Metabolic Process
Activation Of Phospholipase C Activity
Regulation Of Protein Phosphorylation
Response To Stimulus
Positive Regulation Of Phospholipase C Activity
Regulation Of Endocytosis
Response To Stress
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Phospholipase Activity
Regulation Of Catalytic Activity
Membrane Organization
COPI-coated Vesicle Budding
COPI Coating Of Golgi Vesicle
Regulation Of Phosphorylation
Regulation Of Cellular Process
Cell Surface Receptor Signaling Pathway
Regulation Of Phospholipase Activity
G-protein Coupled Receptor Internalization
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Lipase Activity
Enzyme Linked Receptor Protein Signaling Pathway
Golgi Vesicle Transport
Protein Localization
Golgi Vesicle Budding
Positive Regulation Of Cellular Metabolic Process
Protein Transport
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Ubiquitination
Negative Regulation Of Glucose Transport
Vesicle-mediated Transport
Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway
Establishment Of Protein Localization
Tagcloud
?
abhd5
agpat2
anomaly
atgl
cgi
ctgm
dgat1
diverge
enteropathy
gk
glycerol
gpd1
hsl
ichthyosis
inborn
jordan
lipe
lipodystrophy
loosing
lpin1
lpin2
majeed
nlsd
perilipin
pseudohypertriglyceridemia
rhabdomyolysis
steatosis
tgs
vacuolated
Tagcloud (Difference)
?
abhd5
agpat2
anomaly
atgl
cgi
ctgm
dgat1
diverge
enteropathy
gk
glycerol
gpd1
hsl
ichthyosis
inborn
jordan
lipe
lipodystrophy
loosing
lpin1
lpin2
majeed
nlsd
perilipin
pseudohypertriglyceridemia
rhabdomyolysis
steatosis
tgs
vacuolated
Tagcloud (Intersection)
?