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PNPLA2
Gene Name
patatin-like phospholipase domain containing 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Lipid Particle
Cytosol
Plasma Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Triglyceride Lipase Activity
Biological Process
Phospholipid Metabolic Process
Negative Regulation Of Sequestering Of Triglyceride
Positive Regulation Of Triglyceride Catabolic Process
Triglyceride Catabolic Process
Lipid Storage
Lipid Particle Organization
Acylglycerol Acyl-chain Remodeling
Small Molecule Metabolic Process
Glycerophospholipid Biosynthetic Process
Pathways
Metabolism of lipids and lipoproteins
Acyl chain remodeling of DAG and TAG
Phospholipid metabolism
Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS
Protein-protein Interactions
10 interactors:
ABHD5
ARFGEF2
CYTH2
FAF2
GBF1
MARK3
PHYHIP
SERPINF1
SMAD9
UBE2R2
Entrez ID
57104
HPRD ID
11443
Ensembl ID
ENSG00000177666
Uniprot IDs
Q96AD5
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of ARF Protein Signal Transduction
Regulation Of Catalytic Activity
Positive Regulation Of Hydrolase Activity
Post-Golgi Vesicle-mediated Transport
Cellular Response To Cobalt Ion
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Catalytic Activity
Negative Regulation Of Sequestering Of Triglyceride
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Triglyceride Catabolic Process
Regulation Of GTPase Activity
Mullerian Duct Regression
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Receptor Recycling
Response To Cobalt Ion
Golgi Vesicle Transport
Short-term Memory
COPI-coated Vesicle Budding
Positive Regulation Of Lipoprotein Lipase Activity
COPI Coating Of Golgi Vesicle
Positive Regulation Of Metabolic Process
Tagcloud
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abhd5
agpat2
anomaly
atgl
cgi
ctgm
dgat1
diverge
enteropathy
gk
glycerol
gpd1
hsl
ichthyosis
inborn
jordan
lipe
lipodystrophy
loosing
lpin1
lpin2
majeed
nlsd
perilipin
pseudohypertriglyceridemia
rhabdomyolysis
steatosis
tgs
vacuolated