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CCDC85B and EPS8
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CCDC85B
EPS8
Gene Name
coiled-coil domain containing 85B
epidermal growth factor receptor pathway substrate 8
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cell Cortex
Postsynaptic Density
N-methyl-D-aspartate Selective Glutamate Receptor Complex
Cell Junction
Growth Cone
Vesicle
Stereocilium
Ruffle Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Actin Binding
SH3/SH2 Adaptor Activity
Protein Binding
Rac GTPase Binding
Biological Process
Transcription, DNA-templated
Cell Differentiation
Negative Regulation Of Cell Growth
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Cell Proliferation
Adult Locomotory Behavior
Regulation Of Cell Shape
Positive Regulation Of Signal Transduction
Exit From Mitosis
Rac Protein Signal Transduction
Regulation Of Actin Filament Length
Actin Cytoskeleton Reorganization
Dendritic Cell Migration
Behavioral Response To Ethanol
Barbed-end Actin Filament Capping
Actin Filament Bundle Assembly
Actin Crosslink Formation
Actin Polymerization-dependent Cell Motility
Pathways
Drugs
Diseases
GWAS
Protein quantitative trait loci (
18464913
)
Protein-Protein Interactions
133 interactors:
AGGF1
AKAP17A
AKIRIN2
ALS2CR11
APEX2
AQP1
BEX2
C10orf10
C19orf25
C1orf111
C20orf195
C21orf91
C7orf50
C8orf48
CARD9
CCDC112
CCDC116
CCDC120
CCDC185
CCDC33
CCDC67
CCNK
CDK18
CDKN1A
CEP70
CFAP53
CHCHD3
COPS4
CWC25
DOK5
DTNB
DUSP13
EIF3H
ENKD1
EPS8
EXOC7
EXOC8
EZH2
FAM107A
FAM124B
FAM13C
FAM208B
FAM214B
FAM27E3
FAM50B
FAM74A4
FASTKD5
FBF1
FCHSD2
FXR2
GCC1
GFI1B
GPANK1
HMG20B
HNRNPC
IKZF5
KANSL1
KIAA0408
KRT17
KRT18
KRT20
KRT6A
LDOC1
LMO3
LNX1
LZTS2
MBIP
MCM10
MCRS1
MEAF6
MOAP1
MOB1A
MOB4
NDUFA5
NEK6
NGFRAP1
NIF3L1
NRIP1
NUP54
PBXIP1
PIDD1
PKN1
PLEKHF2
PLOD3
POLR2L
PRC1
PRPF3
PSMA1
PSMC1
PSMC6
PSMF1
RALYL
RBM41
RBM7
RIBC2
RNF8
SCNM1
SETD5
SF3A3
SIX1
SLU7
SMARCD1
SYT17
SYTL4
TCEANC
TCHP
TEAD4
THAP7
TNNI1
TNNT1
TSPYL4
TTC14
TTC25
TUBGCP4
USP2
UTP14A
UTP6
VPS72
ZBTB16
ZBTB5
ZC2HC1C
ZFC3H1
ZFP36
ZNF165
ZNF205
ZNF250
ZNF337
ZNF417
ZNF426
ZNF564
ZNF638
ZNF764
ZNF821
54 interactors:
ABI1
ACTA1
ADAM22
AIMP2
ALDH7A1
ARMC1
BAIAP2
BCKDK
BLOC1S6
BYSL
C17orf59
C19orf25
C8orf33
CASK
CCDC85B
CSNK2B
CTNNA3
CXCL2
DNALI1
DVL1
EGFR
GOLGA8EP
GRB2
GULP1
HNRNPC
HOOK2
INPP5J
ITGB1
ITGB3
ITGB5
MAP1LC3B
MAP3K11
MRPL20
MYO15A
NACC2
NFKB2
PCM1
PROSER2
RFXAP
RUNX1T1
SCRN3
SF3B3
SHB
SHC1
SLC27A4
SMARCE1
SOS1
SRC
TDP2
TEX28
TPRN
USP6NL
XRCC6
ZZZ3
Entrez ID
11007
2059
HPRD ID
16101
02563
Ensembl ID
ENSG00000175602
ENSG00000151491
Uniprot IDs
Q15834
B4DX66
B4E3T6
Q12929
PDB IDs
2E8M
Enriched GO Terms of Interacting Partners
?
Gene Expression
RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cell Cycle
RNA Biosynthetic Process
Transcription, DNA-templated
Mitotic Cell Cycle Process
Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Signal Transduction Involved In DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Regulation Of Gene Expression
Signal Transduction Involved In Cell Cycle Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Mitotic G1 DNA Damage Checkpoint
Organelle Organization
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Cellular Metabolic Process
Positive Regulation Of Cell Cycle Arrest
Cell Cycle Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Transcription, DNA-templated
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Apoptotic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of RNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Programmed Cell Death
DNA Damage Checkpoint
Regulation Of Mitotic Cell Cycle Phase Transition
RNA Processing
Mitotic DNA Integrity Checkpoint
Cellular Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Cell Cycle Phase Transition
Cell Death
Cell Differentiation
Developmental Process
Movement Of Cell Or Subcellular Component
Multicellular Organismal Development
System Development
Anatomical Structure Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Axonogenesis
Axon Guidance
Fc Receptor Signaling Pathway
Axon Development
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell Projection Organization
Cell Morphogenesis Involved In Neuron Differentiation
Anatomical Structure Morphogenesis
Chemotaxis
Neurogenesis
Neuron Projection Development
Immune Response-regulating Signaling Pathway
Neuron Projection Morphogenesis
Organelle Organization
Positive Regulation Of Signal Transduction
Cell Morphogenesis
Leukocyte Migration
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Generation Of Neurons
Cell Development
Response To External Stimulus
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cell Morphogenesis Involved In Differentiation
Neuron Development
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Blood Coagulation
Fibroblast Growth Factor Receptor Signaling Pathway
Hemostasis
Regulation Of ERBB Signaling Pathway
Nervous System Development
Innate Immune Response
Anatomical Structure Formation Involved In Morphogenesis
Regulation Of Protein Phosphorylation
Cellular Response To Fibroblast Growth Factor Stimulus
Regulation Of Phosphorylation
Regulation Of Immune System Process
Platelet Activation
Response To Fibroblast Growth Factor
Tagcloud
?
adjacent
breast
cadherin
cisplatin
colony
ectopic
egf
emt
erk
filopodia
g418
healing
invasive
knockdown
lentiviral
mb231
mb468
mcf7
mda
mmp9
mtt
overexpressed
possibly
shrna
stably
transition
vimentin
weakly
wound
Tagcloud (Difference)
?
adjacent
breast
cadherin
cisplatin
colony
ectopic
egf
emt
erk
filopodia
g418
healing
invasive
knockdown
lentiviral
mb231
mb468
mcf7
mda
mmp9
mtt
overexpressed
possibly
shrna
stably
transition
vimentin
weakly
wound
Tagcloud (Intersection)
?