CCDC85B and IKZF5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		CCDC85B	IKZF5
Description		coiled-coil domain containing 85B	IKAROS family zinc finger 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytoskeleton Adherens Junction Anchoring Junction	Nucleus Protein-containing Complex
	Molecular Function	Protein Binding Delta-catenin Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of DNA-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		138 interacting genes: AGGF1 AKAP17A AKIRIN2 APEX2 AQP1 ATOSB BEX2 BEX3 BIRC5 C19orf25 C21orf91 C8orf48 CARD9 CATSPERT CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCNK CDK18 CDKN1A CENPP CEP70 CFAP53 CHCHD3 CHLSN COPS4 CWC25 DEPP1 DEUP1 DOK5 DTNB DUSP13B EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FNDC11 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 INO80B KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NIF3L1 NRIP1 NUP54 ODAD4 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RGS8 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SPATA46 SYT17 SYTL4 TASOR2 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF587 ZNF638 ZNF764 ZNF821	9 interacting genes: CCDC85B IKZF1 IKZF2 IKZF3 IKZF4 LDOC1 NUDT22 PIAS1 UBE2I
Entrez ID		11007	64376
HPRD ID		16101	05873
Ensembl ID		ENSG00000175602	ENSG00000095574
Uniprot IDs		Q15834	Q9H5V7
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus Nuclear Speck Zinc Ion Binding Spindle Pole Spindle Midzone Assembly Keratin Filament Chromatin Organization Regulation Of RNA Metabolic Process	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Presynaptic Cytosol Postsynaptic Cytosol SUMO Transferase Activity Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Protein Domain Specific Binding DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process Protein Sumoylation Mesoderm Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II SUMO Conjugating Enzyme Activity GDP-mannose Hydrolase Activity Nucleoplasm RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding UDP-sugar Diphosphatase Activity PML Body RING-like Zinc Finger Domain Binding Zinc Ion Binding SUMO Ligase Complex HLH Domain Binding Nucleus DNA Binding Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Small Protein Activating Enzyme Binding Maternal Process Involved In Parturition Regulation Of Primary Metabolic Process Negative Regulation Of Biosynthetic Process Metal Ion Binding Delta-catenin Binding Mitotic Nuclear Membrane Reassembly Maternal Placenta Development Cellular Response To Muramyl Dipeptide Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Transferase Complex SUMO Ligase Activity Positive Regulation Of Protein Sumoylation Lymphocyte Differentiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process
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