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CCDC85B and ZFP36
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CCDC85B
ZFP36
Gene Name
coiled-coil domain containing 85B
ZFP36 ring finger protein
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Nucleus
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Molecular Function
Protein Binding
DNA Binding
Single-stranded RNA Binding
MRNA Binding
Protein Binding
AU-rich Element Binding
Enzyme Binding
Protein Kinase Binding
C-C Chemokine Binding
MRNA 3'-UTR AU-rich Region Binding
Poly(A) RNA Binding
Metal Ion Binding
14-3-3 Protein Binding
Biological Process
Transcription, DNA-templated
Cell Differentiation
Negative Regulation Of Cell Growth
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Poly(A) Tail Shortening
MRNA Catabolic Process
Gene Expression
Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Translation Involved In Gene Silencing By MiRNA
Intracellular Signal Transduction
Response To Starvation
Negative Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Inflammatory Response
RNA Destabilization
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
3'-UTR-mediated MRNA Stabilization
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways
Regulation of mRNA stability by proteins that bind AU-rich elements
Tristetraprolin (TTP) destabilizes mRNA
Drugs
Diseases
GWAS
Protein-Protein Interactions
133 interactors:
AGGF1
AKAP17A
AKIRIN2
ALS2CR11
APEX2
AQP1
BEX2
C10orf10
C19orf25
C1orf111
C20orf195
C21orf91
C7orf50
C8orf48
CARD9
CCDC112
CCDC116
CCDC120
CCDC185
CCDC33
CCDC67
CCNK
CDK18
CDKN1A
CEP70
CFAP53
CHCHD3
COPS4
CWC25
DOK5
DTNB
DUSP13
EIF3H
ENKD1
EPS8
EXOC7
EXOC8
EZH2
FAM107A
FAM124B
FAM13C
FAM208B
FAM214B
FAM27E3
FAM50B
FAM74A4
FASTKD5
FBF1
FCHSD2
FXR2
GCC1
GFI1B
GPANK1
HMG20B
HNRNPC
IKZF5
KANSL1
KIAA0408
KRT17
KRT18
KRT20
KRT6A
LDOC1
LMO3
LNX1
LZTS2
MBIP
MCM10
MCRS1
MEAF6
MOAP1
MOB1A
MOB4
NDUFA5
NEK6
NGFRAP1
NIF3L1
NRIP1
NUP54
PBXIP1
PIDD1
PKN1
PLEKHF2
PLOD3
POLR2L
PRC1
PRPF3
PSMA1
PSMC1
PSMC6
PSMF1
RALYL
RBM41
RBM7
RIBC2
RNF8
SCNM1
SETD5
SF3A3
SIX1
SLU7
SMARCD1
SYT17
SYTL4
TCEANC
TCHP
TEAD4
THAP7
TNNI1
TNNT1
TSPYL4
TTC14
TTC25
TUBGCP4
USP2
UTP14A
UTP6
VPS72
ZBTB16
ZBTB5
ZC2HC1C
ZFC3H1
ZFP36
ZNF165
ZNF205
ZNF250
ZNF337
ZNF417
ZNF426
ZNF564
ZNF638
ZNF764
ZNF821
22 interactors:
APP
CCDC85B
CDK6
DCP1B
DHX36
DNAJB1
EDC3
EXOSC6
EXOSC8
HMGB1
HOXC9
MAPK1
MAPKAPK2
NCL
NUP214
SFN
UPF2
XRN1
YWHAB
YWHAG
YWHAH
ZDHHC17
Entrez ID
11007
7538
HPRD ID
16101
01835
Ensembl ID
ENSG00000175602
ENSG00000128016
Uniprot IDs
Q15834
M0QY76
P26651
PDB IDs
4J8S
Enriched GO Terms of Interacting Partners
?
Gene Expression
RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cell Cycle
RNA Biosynthetic Process
Transcription, DNA-templated
Mitotic Cell Cycle Process
Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Signal Transduction Involved In DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Regulation Of Gene Expression
Signal Transduction Involved In Cell Cycle Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Mitotic G1 DNA Damage Checkpoint
Organelle Organization
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Cellular Metabolic Process
Positive Regulation Of Cell Cycle Arrest
Cell Cycle Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Transcription, DNA-templated
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Apoptotic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of RNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Programmed Cell Death
DNA Damage Checkpoint
Regulation Of Mitotic Cell Cycle Phase Transition
RNA Processing
Mitotic DNA Integrity Checkpoint
Cellular Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Cell Cycle Phase Transition
Cell Death
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
MRNA Catabolic Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Catabolic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Aromatic Compound Catabolic Process
Gene Expression
Positive Regulation Of Mitochondrion Organization
MRNA Metabolic Process
RNA Metabolic Process
Regulation Of Mitochondrion Organization
Regulation Of Cellular Response To Heat
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Catabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
System Development
Apoptotic Process
Cellular Nitrogen Compound Metabolic Process
Programmed Cell Death
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cellular Component Organization
Positive Regulation Of Organelle Organization
Cell Death
Death
Cellular Metabolic Process
Cellular Response To Heat
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Intracellular Transport
Regulation Of Protein Kinase Activity
Developmental Process
Nitrogen Compound Metabolic Process
Multicellular Organismal Development
Regulation Of Kinase Activity
Positive Regulation Of Intracellular Transport
Innate Immune Response
Anatomical Structure Development
Positive Regulation Of Signal Transduction
Immune Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Catabolic Process
Regulation Of Organelle Organization
Regulation Of Catalytic Activity
Response To Heat
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Tagcloud
?
annotation
bub
california
cruz
databases
david
deterioration
downloaded
exploring
geo
gse27567
h17
hub
inheritance
mendelian
networks
omim
omnibus
ranked
santa
topological
visualization
xpc
xrcc4
xrcc5
ybx1
yy1
zfhx3
zmat3
Tagcloud (Difference)
?
annotation
bub
california
cruz
databases
david
deterioration
downloaded
exploring
geo
gse27567
h17
hub
inheritance
mendelian
networks
omim
omnibus
ranked
santa
topological
visualization
xpc
xrcc4
xrcc5
ybx1
yy1
zfhx3
zmat3
Tagcloud (Intersection)
?