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CCDC85B and CCNK
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CCDC85B
CCNK
Gene Name
coiled-coil domain containing 85B
cyclin K
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cyclin K-CDK12 Complex
Cyclin K-CDK13 Complex
Nucleus
Molecular Function
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
Protein Kinase Binding
Biological Process
Transcription, DNA-templated
Cell Differentiation
Negative Regulation Of Cell Growth
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
In Utero Embryonic Development
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Mitotic Nuclear Division
Cell Division
Negative Regulation Of Cell Cycle Arrest
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
133 interactors:
AGGF1
AKAP17A
AKIRIN2
ALS2CR11
APEX2
AQP1
BEX2
C10orf10
C19orf25
C1orf111
C20orf195
C21orf91
C7orf50
C8orf48
CARD9
CCDC112
CCDC116
CCDC120
CCDC185
CCDC33
CCDC67
CCNK
CDK18
CDKN1A
CEP70
CFAP53
CHCHD3
COPS4
CWC25
DOK5
DTNB
DUSP13
EIF3H
ENKD1
EPS8
EXOC7
EXOC8
EZH2
FAM107A
FAM124B
FAM13C
FAM208B
FAM214B
FAM27E3
FAM50B
FAM74A4
FASTKD5
FBF1
FCHSD2
FXR2
GCC1
GFI1B
GPANK1
HMG20B
HNRNPC
IKZF5
KANSL1
KIAA0408
KRT17
KRT18
KRT20
KRT6A
LDOC1
LMO3
LNX1
LZTS2
MBIP
MCM10
MCRS1
MEAF6
MOAP1
MOB1A
MOB4
NDUFA5
NEK6
NGFRAP1
NIF3L1
NRIP1
NUP54
PBXIP1
PIDD1
PKN1
PLEKHF2
PLOD3
POLR2L
PRC1
PRPF3
PSMA1
PSMC1
PSMC6
PSMF1
RALYL
RBM41
RBM7
RIBC2
RNF8
SCNM1
SETD5
SF3A3
SIX1
SLU7
SMARCD1
SYT17
SYTL4
TCEANC
TCHP
TEAD4
THAP7
TNNI1
TNNT1
TSPYL4
TTC14
TTC25
TUBGCP4
USP2
UTP14A
UTP6
VPS72
ZBTB16
ZBTB5
ZC2HC1C
ZFC3H1
ZFP36
ZNF165
ZNF205
ZNF250
ZNF337
ZNF417
ZNF426
ZNF564
ZNF638
ZNF764
ZNF821
26 interactors:
AES
ATXN1
BHLHE40
CCDC85B
CDK18
CDK2
CDK9
CEP76
DVL3
EFEMP2
FKBP6
HMG20A
KCNRG
KRTAP4-12
LZTS2
NDC80
NECAB2
PIN1
POLR2A
RBPMS
RFX6
RHOXF2
STX11
TSC22D4
UBC
USHBP1
Entrez ID
11007
8812
HPRD ID
16101
10352
Ensembl ID
ENSG00000175602
Uniprot IDs
Q15834
O75909
PDB IDs
2I53
Enriched GO Terms of Interacting Partners
?
Gene Expression
RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cell Cycle
RNA Biosynthetic Process
Transcription, DNA-templated
Mitotic Cell Cycle Process
Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Signal Transduction Involved In DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Regulation Of Gene Expression
Signal Transduction Involved In Cell Cycle Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Mitotic G1 DNA Damage Checkpoint
Organelle Organization
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Cellular Metabolic Process
Positive Regulation Of Cell Cycle Arrest
Cell Cycle Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Transcription, DNA-templated
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Apoptotic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of RNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Programmed Cell Death
DNA Damage Checkpoint
Regulation Of Mitotic Cell Cycle Phase Transition
RNA Processing
Mitotic DNA Integrity Checkpoint
Cellular Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Cell Cycle Phase Transition
Cell Death
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Wnt Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle Process
Regulation Of Ubiquitin-protein Transferase Activity
Heterocycle Metabolic Process
Regulation Of Cell Cycle Arrest
Cellular Aromatic Compound Metabolic Process
Gene Expression
Regulation Of Metabolic Process
Regulation Of Wnt Signaling Pathway
Regulation Of Cell Cycle
Cell Cycle
Cellular Nitrogen Compound Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cellular Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Mitotic Cell Cycle Process
Positive Regulation Of Gene Expression
Negative Regulation Of Signal Transduction
PiRNA Metabolic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Mitotic Cell Cycle
Biosynthetic Process
Negative Regulation Of Signaling
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Viral Transcription
Regulation Of Protein Ubiquitination
Tagcloud
?
affects
associate
bulk
cdk12
cdk13
cdk9
cdks
ctd
elongation
far
flag
hct116
heptad
implementing
numerous
paralog
partner
phosphorylate
preferentially
processing
repeat
reveals
rna
sec
seq
snorna
super
tagged
tefb
Tagcloud (Difference)
?
affects
associate
bulk
cdk12
cdk13
cdk9
cdks
ctd
elongation
far
flag
hct116
heptad
implementing
numerous
paralog
partner
phosphorylate
preferentially
processing
repeat
reveals
rna
sec
seq
snorna
super
tagged
tefb
Tagcloud (Intersection)
?