CCDC85B and TEAD4

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCDC85B	TEAD4
Gene Name		coiled-coil domain containing 85B	TEA domain family member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Centrosome	Nucleoplasm
	Molecular Function	Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Skeletal System Development Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Muscle Organ Development Gene Expression Hippo Signaling
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS			Narcolepsy with cataplexy ( 23496005)
Protein-Protein Interactions		133 interactors: AGGF1 AKAP17A AKIRIN2 ALS2CR11 APEX2 AQP1 BEX2 C10orf10 C19orf25 C1orf111 C20orf195 C21orf91 C7orf50 C8orf48 CARD9 CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCDC67 CCNK CDK18 CDKN1A CEP70 CFAP53 CHCHD3 COPS4 CWC25 DOK5 DTNB DUSP13 EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM208B FAM214B FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NGFRAP1 NIF3L1 NRIP1 NUP54 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SYT17 SYTL4 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TTC25 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF638 ZNF764 ZNF821	18 interactors: CCDC172 CCDC85B CCNDBP1 CEP55 CEP70 GOLGA2 KIAA0753 LZTS2 MYH7 PNMA1 RABGEF1 SSX2IP TRAF1 TRIM27 VGLL1 VPS52 WWTR1 YAP1
Entrez ID		11007	7004
HPRD ID		16101	03421
Ensembl ID		ENSG00000175602	ENSG00000197905
Uniprot IDs		Q15834	D3DUQ6 Q15561
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Cycle RNA Biosynthetic Process Transcription, DNA-templated Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Regulation Of Cell Cycle Arrest Regulation Of Gene Expression Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Mitotic G1 DNA Damage Checkpoint Organelle Organization Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Metabolic Process Positive Regulation Of Cell Cycle Arrest Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Apoptotic Process Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Process Programmed Cell Death DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition RNA Processing Mitotic DNA Integrity Checkpoint Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Cell Death	Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Hippo Signaling Negative Regulation Of Protein Transport Negative Regulation Of Cytokine Secretion Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Stem Cell Differentiation Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Kit Signaling Pathway Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Phosphorylation Mitotic Cell Cycle Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Interleukin-2 Secretion Embryonic Ectodermal Digestive Tract Development Cell Cycle Regulation Of Protein Localization Negative Regulation Of Protein Secretion Negative Regulation Of Transport Negative Regulation Of Phosphorylation Cytokinesis Cell Division Negative Regulation Of Intracellular Transport Regulation Of Fat Cell Differentiation Negative Regulation Of Immune Response Negative Regulation Of Interleukin-6 Secretion Negative Regulation Of Mast Cell Degranulation Regulation Of Cytokine Secretion Regulation Of Epithelial Cell Differentiation Negative Regulation Of Calcium Ion Import Negative Regulation Of Mast Cell Activation Involved In Immune Response Intraciliary Transport Involved In Cilium Morphogenesis Ectodermal Cell Differentiation Regulation Of Cellular Localization Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of Stem Cell Maintenance Negative Regulation Of Secretion By Cell Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Interferon-gamma Secretion Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Protein Ubiquitination Negative Regulation Of Secretion Negative Regulation Of Signaling Regulation Of Signal Transduction Spindle Midzone Assembly Protein Modification By Small Protein Conjugation
Tagcloud ?			amphibian amphibians amputation appendage autonomously biol buds dev dnyap epimorphic hayashi hippo organ outgrowth regenerating regeneration regenerative shallow strictly synchronized tadpole tail terminates vertebrate xenopus yap yap1
Tagcloud (Difference) ?			amphibian amphibians amputation appendage autonomously biol buds dev dnyap epimorphic hayashi hippo organ outgrowth regenerating regeneration regenerative shallow strictly synchronized tadpole tail terminates vertebrate xenopus yap yap1
Tagcloud (Intersection) ?