CCDC85B and PRC1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		CCDC85B	PRC1
Gene Name		coiled-coil domain containing 85B	protein regulator of cytokinesis 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Centrosome	Spindle Pole Nucleus Nucleoplasm Cytoplasm Spindle Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding Identical Protein Binding
	Biological Process	Transcription, DNA-templated Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Mitotic Spindle Elongation Cytokinesis
Pathways
Drugs
Diseases
GWAS			Type 2 diabetes ( 20581827)
Protein-Protein Interactions		133 interactors: AGGF1 AKAP17A AKIRIN2 ALS2CR11 APEX2 AQP1 BEX2 C10orf10 C19orf25 C1orf111 C20orf195 C21orf91 C7orf50 C8orf48 CARD9 CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCDC67 CCNK CDK18 CDKN1A CEP70 CFAP53 CHCHD3 COPS4 CWC25 DOK5 DTNB DUSP13 EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM208B FAM214B FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NGFRAP1 NIF3L1 NRIP1 NUP54 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SYT17 SYTL4 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TTC25 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF638 ZNF764 ZNF821	12 interactors: CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 KIF4A KRT20 PLK1 RACGAP1 TRIM37 USHBP1
Entrez ID		11007	9055
HPRD ID		16101	17899
Ensembl ID		ENSG00000175602	ENSG00000198901
Uniprot IDs		Q15834	F8W9B5 O43663
PDB IDs			3NRX 3NRY 4L3I 4L6Y
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Cycle RNA Biosynthetic Process Transcription, DNA-templated Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Regulation Of Cell Cycle Arrest Regulation Of Gene Expression Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Mitotic G1 DNA Damage Checkpoint Organelle Organization Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Metabolic Process Positive Regulation Of Cell Cycle Arrest Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Apoptotic Process Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Process Programmed Cell Death DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition RNA Processing Mitotic DNA Integrity Checkpoint Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Cell Death	Cell Division Mitotic Nuclear Division Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cell Cycle G2/M Transition Of Mitotic Cell Cycle Cell Cycle Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Process Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Cell Cycle G2 DNA Damage Checkpoint Mitotic Nuclear Envelope Disassembly DNA Damage Checkpoint G1/S Transition Of Mitotic Cell Cycle Organelle Organization Regulation Of Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint Histone Phosphorylation Nuclear Envelope Disassembly Microtubule Cytoskeleton Organization Negative Regulation Of Cell Cycle Mitotic Cytokinesis Regulation Of Protein Ubiquitination Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Cell Cycle Checkpoint Mitotic Spindle Midzone Assembly Nuclear Envelope Organization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cytoskeleton Organization Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic Spindle Elongation Positive Regulation Of Ligase Activity Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Response To Wounding Spindle Midzone Assembly Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Mitotic DNA Damage Checkpoint Regulation Of Protein Kinase Activity Centrosome Organization Mitotic DNA Integrity Checkpoint Microtubule-based Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Tagcloud ?			activates autism auts2 candidate canonical chip ck2 cns comprise conditional developmental disrupted immunoprecipitation leads linking modulators naturally nervous neurodevelopment neuronal neutralizes occurring polycomb repression repressive seq subverting surprisingly variations
Tagcloud (Difference) ?			activates autism auts2 candidate canonical chip ck2 cns comprise conditional developmental disrupted immunoprecipitation leads linking modulators naturally nervous neurodevelopment neuronal neutralizes occurring polycomb repression repressive seq subverting surprisingly variations
Tagcloud (Intersection) ?