CCDC85B and FAM124B

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		CCDC85B	FAM124B
Gene Name		coiled-coil domain containing 85B	family with sequence similarity 124B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Centrosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		133 interactors: AGGF1 AKAP17A AKIRIN2 ALS2CR11 APEX2 AQP1 BEX2 C10orf10 C19orf25 C1orf111 C20orf195 C21orf91 C7orf50 C8orf48 CARD9 CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCDC67 CCNK CDK18 CDKN1A CEP70 CFAP53 CHCHD3 COPS4 CWC25 DOK5 DTNB DUSP13 EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM208B FAM214B FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NGFRAP1 NIF3L1 NRIP1 NUP54 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SYT17 SYTL4 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TTC25 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF638 ZNF764 ZNF821	29 interactors: ADAMTSL4 AES BIRC7 CARD9 CCDC85B EFEMP2 GOLGA2 KCTD6 KCTD9 KIAA1958 KRT19 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LZTS2 MDFI MKRN3 NOTCH2NL RBPMS RINT1 SSX2IP TCF4 TRIM37 TRIM54 TRIP6 USHBP1
Entrez ID		11007	79843
HPRD ID		16101	08663
Ensembl ID		ENSG00000175602	ENSG00000124019
Uniprot IDs		Q15834	Q9H5Z6
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Cycle RNA Biosynthetic Process Transcription, DNA-templated Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Regulation Of Cell Cycle Arrest Regulation Of Gene Expression Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Mitotic G1 DNA Damage Checkpoint Organelle Organization Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Metabolic Process Positive Regulation Of Cell Cycle Arrest Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Apoptotic Process Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Process Programmed Cell Death DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition RNA Processing Mitotic DNA Integrity Checkpoint Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Cell Death	Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Transport Regulation Of Binding Regulation Of Intracellular Protein Transport Negative Regulation Of Binding Regulation Of Signal Transduction Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Wnt Signaling Pathway Positive Regulation Of JNK Cascade Cellular Component Assembly Regulation Of Signaling Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Cellular Localization Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Binding Cell Differentiation Involved In Embryonic Placenta Development Positive Regulation Of Intracellular Protein Transport Regulation Of JNK Cascade Activation Of JUN Kinase Activity Regulation Of Protein Import Into Nucleus Regulation Of Stress-activated MAPK Cascade Regulation Of Protein Localization Positive Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Natural Killer Cell Apoptotic Process Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Binding Positive Regulation Of Intracellular Transport Negative Regulation Of Fat Cell Differentiation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of JUN Kinase Activity Wnt Signaling Pathway Regulation Of Protein Transport Negative Regulation Of Protein Localization To Nucleus Regulation Of JUN Kinase Activity Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Histone H2A-K119 Monoubiquitination JNK Cascade Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription Factor Import Into Nucleus Regulation Of Establishment Of Protein Localization Negative Regulation Of RNA Biosynthetic Process Maintenance Of DNA Repeat Elements
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