CCDC85B and CWC25

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		CCDC85B	CWC25
Description		coiled-coil domain containing 85B	CWC25 spliceosome associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytoskeleton Adherens Junction Anchoring Junction	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex Nuclear Speck U2-type Catalytic Step 1 Spliceosome
	Molecular Function	Protein Binding Delta-catenin Binding	Protein Binding
	Biological Process	Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of DNA-templated Transcription	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Hip circumference adjusted for BMI ( 34021172)	Intraocular pressure ( 29617998)
Interacting Genes		138 interacting genes: AGGF1 AKAP17A AKIRIN2 APEX2 AQP1 ATOSB BEX2 BEX3 BIRC5 C19orf25 C21orf91 C8orf48 CARD9 CATSPERT CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCNK CDK18 CDKN1A CENPP CEP70 CFAP53 CHCHD3 CHLSN COPS4 CWC25 DEPP1 DEUP1 DOK5 DTNB DUSP13B EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FNDC11 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 INO80B KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NIF3L1 NRIP1 NUP54 ODAD4 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RGS8 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SPATA46 SYT17 SYTL4 TASOR2 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF587 ZNF638 ZNF764 ZNF821	7 interacting genes: CCDC85B FMR1 KRT34 LAMC3 MDM2 OGT TRIM21
Entrez ID		11007	54883
HPRD ID		16101	07892
Ensembl ID		ENSG00000175602	ENSG00000273559
Uniprot IDs		Q15834	Q9NXE8
PDB IDs			5YZG 6ZYM 8I0W
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus Nuclear Speck Zinc Ion Binding Spindle Pole Spindle Midzone Assembly Keratin Filament Chromatin Organization Regulation Of RNA Metabolic Process	Pyroptotic Inflammatory Response Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Viral Life Cycle Negative Regulation Of Protein Metabolic Process Stress Granule Assembly Cellular Response To Nutrient Negative Regulation Of Translational Initiation Membraneless Organelle Assembly Positive Regulation Of Viral Process Positive Regulation Of Intracellular Transport Of Viral Material Response To Formaldehyde Protein Autoubiquitination Cellular Response To Vitamin B1 Protein Destabilization Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Protein Catabolic Process Regulation Of Receptor Internalization Regulation Of Proteolysis Cytoplasmic Stress Granule Negative Regulation Of Post-translational Protein Modification Dendritic Filopodium Histone H3 Reader Activity Cytotoxic T Cell Pyroptotic Cell Death Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Negative Regulation Of Long-term Synaptic Depression Regulation Of Viral Life Cycle Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Translational Initiation Response To Vitamin B1 Response To Water-immersion Restraint Stress Cellular Response To Actinomycin D Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Viral Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process NEDD8 Ligase Activity Response To Actinomycin D Negative Regulation Of Proteolysis Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Inflammatory Response Negative Regulation Of Protein Deubiquitination Response To Nutrient RNA Strand Annealing Activity Regulation Of Neuronal Action Potential
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