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CCDC85B and KRT17
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
HPRD
(two hybrid)
CCDC85B
KRT17
Gene Name
coiled-coil domain containing 85B
keratin 17, type I
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cytoplasm
Intermediate Filament
Extracellular Vesicular Exosome
Cell Periphery
Molecular Function
Protein Binding
Structural Constituent Of Cytoskeleton
Protein Binding
MHC Class II Receptor Activity
MHC Class II Protein Binding
Biological Process
Transcription, DNA-templated
Cell Differentiation
Negative Regulation Of Cell Growth
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Signal Transduction
Epidermis Development
Positive Regulation Of Cell Growth
Hair Follicle Morphogenesis
Keratinization
Intermediate Filament Organization
Positive Regulation Of Translation
Positive Regulation Of Hair Follicle Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
133 interactors:
AGGF1
AKAP17A
AKIRIN2
ALS2CR11
APEX2
AQP1
BEX2
C10orf10
C19orf25
C1orf111
C20orf195
C21orf91
C7orf50
C8orf48
CARD9
CCDC112
CCDC116
CCDC120
CCDC185
CCDC33
CCDC67
CCNK
CDK18
CDKN1A
CEP70
CFAP53
CHCHD3
COPS4
CWC25
DOK5
DTNB
DUSP13
EIF3H
ENKD1
EPS8
EXOC7
EXOC8
EZH2
FAM107A
FAM124B
FAM13C
FAM208B
FAM214B
FAM27E3
FAM50B
FAM74A4
FASTKD5
FBF1
FCHSD2
FXR2
GCC1
GFI1B
GPANK1
HMG20B
HNRNPC
IKZF5
KANSL1
KIAA0408
KRT17
KRT18
KRT20
KRT6A
LDOC1
LMO3
LNX1
LZTS2
MBIP
MCM10
MCRS1
MEAF6
MOAP1
MOB1A
MOB4
NDUFA5
NEK6
NGFRAP1
NIF3L1
NRIP1
NUP54
PBXIP1
PIDD1
PKN1
PLEKHF2
PLOD3
POLR2L
PRC1
PRPF3
PSMA1
PSMC1
PSMC6
PSMF1
RALYL
RBM41
RBM7
RIBC2
RNF8
SCNM1
SETD5
SF3A3
SIX1
SLU7
SMARCD1
SYT17
SYTL4
TCEANC
TCHP
TEAD4
THAP7
TNNI1
TNNT1
TSPYL4
TTC14
TTC25
TUBGCP4
USP2
UTP14A
UTP6
VPS72
ZBTB16
ZBTB5
ZC2HC1C
ZFC3H1
ZFP36
ZNF165
ZNF205
ZNF250
ZNF337
ZNF417
ZNF426
ZNF564
ZNF638
ZNF764
ZNF821
10 interactors:
APC
CCDC85B
EGFR
KDM1A
KRT6A
KRT7
KRT72
KRT8
TRIM69
ZDHHC17
Entrez ID
11007
3872
HPRD ID
16101
01019
Ensembl ID
ENSG00000175602
ENSG00000128422
Uniprot IDs
Q15834
Q04695
Q14666
PDB IDs
Enriched GO Terms of Interacting Partners
?
Gene Expression
RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cell Cycle
RNA Biosynthetic Process
Transcription, DNA-templated
Mitotic Cell Cycle Process
Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Signal Transduction Involved In DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Regulation Of Gene Expression
Signal Transduction Involved In Cell Cycle Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Mitotic G1 DNA Damage Checkpoint
Organelle Organization
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Cellular Metabolic Process
Positive Regulation Of Cell Cycle Arrest
Cell Cycle Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Transcription, DNA-templated
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Apoptotic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of RNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Programmed Cell Death
DNA Damage Checkpoint
Regulation Of Mitotic Cell Cycle Phase Transition
RNA Processing
Mitotic DNA Integrity Checkpoint
Cellular Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Cell Cycle Phase Transition
Cell Death
Alkanesulfonate Metabolic Process
Regulation Of Primitive Erythrocyte Differentiation
Negative Regulation Of Chromosome Organization
Hair Follicle Development
Hair Cycle Process
Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process
Astrocyte Activation
Hair Cycle
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Gland Development
Embryonic Placenta Development
In Utero Embryonic Development
Cell Differentiation
Negative Regulation Of Protein Catabolic Process
Regulation Of Response To DNA Damage Stimulus
Activation Of Phospholipase A2 Activity
Negative Regulation Of Odontogenesis
Positive Regulation Of Phospholipase A2 Activity
Muscle Cell Development
Regulation Of Cell Proliferation
Regulation Of Myeloid Cell Differentiation
Response To Cobalamin
Response To UV-A
Placenta Development
Response To Hydroxyisoflavone
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Histone H3-K9 Demethylation
Positive Regulation Of Superoxide Anion Generation
Negative Regulation Of Histone H3-K4 Methylation
Response To Hydrostatic Pressure
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle
Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process
Histone H3-K4 Demethylation
Regulation Of Chromosome Organization
Tagcloud
?
aggressiveness
axis
basal
blbc
comprised
concurrent
cytokeratin
cytokeratins
cytoskeleton
erk1
gaba
gabrp
hcc1187
hcc70
inherent
krt14
krt5
krt6b
maintains
migratory
poorer
postulate
protrusions
silenced
stably
subtype
therapeutics
tn
tumorigenic
Tagcloud (Difference)
?
aggressiveness
axis
basal
blbc
comprised
concurrent
cytokeratin
cytokeratins
cytoskeleton
erk1
gaba
gabrp
hcc1187
hcc70
inherent
krt14
krt5
krt6b
maintains
migratory
poorer
postulate
protrusions
silenced
stably
subtype
therapeutics
tn
tumorigenic
Tagcloud (Intersection)
?