FBLN1 and NEDD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		FBLN1	NEDD1
Gene Name		fibulin 1	neural precursor cell expressed, developmentally down-regulated 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Basement Membrane Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome	Pericentriolar Material Spindle Pole Nucleoplasm Nucleolus Centrosome Centriole Cytosol Plasma Membrane Ciliary Basal Body Apical Part Of Cell
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Peptidase Activator Activity
	Biological Process	Embryo Implantation Positive Regulation Of Peptidase Activity Viral Process Extracellular Matrix Organization	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Cell Division
Pathways		Molecules associated with elastic fibres Elastic fibre formation	Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Recruitment of NuMA to mitotic centrosomes Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Temperament (bipolar disorder) ( 22365631)	Breast size ( 22747683)
Protein-Protein Interactions		35 interactors: ACAN ADAMTSL2 ADAMTSL4 APOA1 APP ATN1 BHLHE40 CACNA1A CTGF ECM1 EDC4 ELN FGB FN1 GFI1B HBEGF HSPG2 ITGB1 LTBP4 MFAP5 MOB4 NEDD1 NID1 NOTCH3 NOV PLSCR1 SKIL SMAD3 SMAD4 TAF9 TANK TCF7L2 TDGF1 VCAN YWHAQ	2 interactors: EP300 FBLN1
Entrez ID		2192	121441
HPRD ID		00629	02655
Ensembl ID		ENSG00000077942	ENSG00000139350
Uniprot IDs		P23142 Q8NBH6	A8K1Z3 G3V3F1 Q8NHV4
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Organ Development Regulation Of Cellular Component Organization System Development Multicellular Organismal Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Anatomical Structure Morphogenesis Anatomical Structure Development Positive Regulation Of Cell-substrate Adhesion Developmental Process Regulation Of Growth Regulation Of Cell Differentiation Regulation Of Cell Development Cardiovascular System Development Regulation Of Cell Growth Regulation Of Signaling Tissue Development Regulation Of Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Cell Death Anatomical Structure Formation Involved In Morphogenesis Transcription Initiation From RNA Polymerase II Promoter Nervous System Development Extracellular Matrix Disassembly Regulation Of Cell-substrate Adhesion Regulation Of Cell Morphogenesis Angiogenesis Positive Regulation Of Cell Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Response To Wounding Blood Vessel Development Vasculature Development Negative Regulation Of Cell Death Central Nervous System Development Regulation Of Protein Metabolic Process DNA-templated Transcription, Initiation Locomotion Positive Regulation Of Intracellular Signal Transduction Response To Growth Factor Wound Healing Negative Regulation Of Signal Transduction Blood Vessel Morphogenesis Positive Regulation Of Cell Differentiation Ossification Transcription From RNA Polymerase II Promoter Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Histone H2B Acetylation N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Tubulin Deacetylation Viral Process Positive Regulation By Host Of Viral Transcription N-terminal Protein Amino Acid Acetylation Regulation Of Androgen Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Interaction With Symbiont Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Viral Transcription Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Protein Deacetylation Histone H4 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Heat Positive Regulation Of Protein Binding Regulation Of Viral Transcription Positive Regulation Of Viral Process Embryo Implantation Positive Regulation Of Type I Interferon Production Regulation Of Cellular Protein Metabolic Process Somitogenesis Protein Stabilization Endoplasmic Reticulum Unfolded Protein Response Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Somite Development Cellular Response To Hypoxia Cellular Response To Unfolded Protein Cellular Response To Decreased Oxygen Levels Regulation Of Protein Metabolic Process ER-nucleus Signaling Pathway Regulation Of Type I Interferon Production Cellular Response To Oxygen Levels Cellular Response To Topologically Incorrect Protein Response To Heat Histone Acetylation Signal Transduction By P53 Class Mediator Segmentation G2/M Transition Of Mitotic Cell Cycle Internal Peptidyl-lysine Acetylation Positive Regulation Of Binding Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation
Tagcloud ?		3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated etv5 exhibits filopodia fmn2 gfra2 gpm6a gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi	amenable angiosperms arabidopsis cytokinesis division extrapolated gcp2 gem1 heterozygous homozygous lethal microgametophytes microspores microtubule mitosis organizing parent phragmoplast pinpoint plane pole pollen reorganization spindle sporophytic structurally take thaliana tubulin
Tagcloud (Difference) ?		3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated etv5 exhibits filopodia fmn2 gfra2 gpm6a gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi	amenable angiosperms arabidopsis cytokinesis division extrapolated gcp2 gem1 heterozygous homozygous lethal microgametophytes microspores microtubule mitosis organizing parent phragmoplast pinpoint plane pole pollen reorganization spindle sporophytic structurally take thaliana tubulin
Tagcloud (Intersection) ?