SOCS3 and PDPK1

  • Number of citations of the paper that reports this interaction (PMID 21900206)
  • 27
  • Data Source:
  • BioGRID (two hybrid)

SOCS3

PDPK1

Gene Name suppressor of cytokine signaling 3 3-phosphoinositide dependent protein kinase 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood trace element (Se levels) ( 23720494)
Protein-Protein Interactions 48 interactors: ACADVL APP BCL10 BIK CSF1R CSF3R CSNK1E CUEDC2 CXCR4 EGFR EPOR GFRA1 GHR HIVEP1 IGF1R IL12RB2 IL2RB IL6ST INSR IRS1 IRS2 JAK1 JAK2 JAK3 KIAA1958 LEPR MAP1S MAPK11 MAPK6 NME4 PDPK1 PIN1 PPP3CB PRLR PTK2 PTPN11 RASA1 RBMX RNF31 RPL7A SOCS2 TCEB1 TCEB2 TES TFDP1 TFR2 TXNDC11 YES1 58 interactors: AKT1 AKT2 AKT3 AKTIP APP BLMH C2orf44 CARD11 CDAN1 DDIT4 FAM213B GIT1 HSP90AA1 ILK IRS1 ITGB3 KATNBL1 LUC7L2 MAPK8 MTOR PAK1 PEA15 PHAX PKN1 PKN2 PNO1 POLDIP2 PRKACA PRKCB PRKCD PRKCE PRKCI PRKCZ PRSS23 PTK2B PXN RALGDS RPS6KA1 RPS6KA3 RPS6KB1 RPS6KB2 SBF1 SGK1 SGK2 SGK3 SLC9A3R2 SMARCB1 SOCS3 SRC SRPK1 STRAP TCAP XPO7 XRCC6 YWHAH YWHAQ ZC3HC1 ZNF133
Entrez ID 9021 5170
HPRD ID 05006 05556
Ensembl ID ENSG00000184557 ENSG00000140992
Uniprot IDs O14543 Q6FI39 E9PER6 O15530
PDB IDs 1H1W 1OKY 1OKZ 1UU3 1UU7 1UU8 1UU9 1UVR 1W1D 1W1G 1W1H 1Z5M 2BIY 2PE0 2PE1 2PE2 2R7B 2VKI 2XCH 2XCK 3H9O 3HRC 3HRF 3ION 3IOP 3NAX 3NAY 3NUN 3NUS 3NUU 3NUY 3ORX 3ORZ 3OTU 3PWY 3QC4 3QCQ 3QCS 3QCX 3QCY 3QD0 3QD3 3QD4 3RCJ 3RWP 3RWQ 3SC1 4A06 4A07 4AW0 4AW1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activates  activator  ameliorate  attenuate  autoimmune  cd25lowcd44lowcd62lhigh  cd4  coculture  enhance  fate  h3k27me3  h3k4me3  immunomodulatory  immunoregulatory  inhibit  interferon  leading  manifestations  mesenchymal  msc  mscs  promoters  reciprocal  rorgammat  stat1  stat3  suppressors  th17  transducer 
amplified  bcl2l1  caspase  caspases  executioner  ikbkb  kinome  mb231  mb468  mesenchymal  nodes  nonkinases  phosphatases  phosphatome  r1  r2  regulators  representing  screens  sensitivities  sensitizes  sineg  sirna  skbr3  src  subset  t47d  tnbc  trail 
Tagcloud (Difference) ?
activates  activator  ameliorate  attenuate  autoimmune  cd25lowcd44lowcd62lhigh  cd4  coculture  enhance  fate  h3k27me3  h3k4me3  immunomodulatory  immunoregulatory  inhibit  interferon  leading  manifestations  msc  mscs  promoters  reciprocal  rorgammat  stat1  stat3  suppressors  th17  transducer 
amplified  bcl2l1  caspase  caspases  executioner  ikbkb  kinome  mb231  mb468  nodes  nonkinases  phosphatases  phosphatome  r1  r2  regulators  representing  screens  sensitivities  sensitizes  sineg  sirna  skbr3  src  subset  t47d  tnbc  trail 
Tagcloud (Intersection) ?
mesenchymal