SOCS3 and IL6ST

  • Number of citations of the paper that reports this interaction (PMID 12403768)
  • 38
  • Data Source:
  • HPRD (in vivo, in vitro)

SOCS3

IL6ST

Gene Name suppressor of cytokine signaling 3 interleukin 6 signal transducer
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood trace element (Se levels) ( 23720494)
Protein-Protein Interactions 48 interactors: ACADVL APP BCL10 BIK CSF1R CSF3R CSNK1E CUEDC2 CXCR4 EGFR EPOR GFRA1 GHR HIVEP1 IGF1R IL12RB2 IL2RB IL6ST INSR IRS1 IRS2 JAK1 JAK2 JAK3 KIAA1958 LEPR MAP1S MAPK11 MAPK6 NME4 PDPK1 PIN1 PPP3CB PRLR PTK2 PTPN11 RASA1 RBMX RNF31 RPL7A SOCS2 TCEB1 TCEB2 TES TFDP1 TFR2 TXNDC11 YES1 31 interactors: AR CDK9 CNTF CNTFR CTF1 ERBB2 ERBB3 HCK IL31RA IL6 IL6R JAK1 KCNIP3 LIF LIFR MAGEA11 OSM OSMR PIK3CG PLAUR PRKCD PTPN11 PTPN6 SGTB SHC1 SOCS3 STAT3 TLE1 TYK2 UBQLN1 VAV1
Entrez ID 9021 3572
HPRD ID 05006 02824
Ensembl ID ENSG00000184557 ENSG00000134352
Uniprot IDs O14543 Q6FI39 D6RH03 P40189 Q17RA0
PDB IDs 1BJ8 1BQU 1I1R 1N2Q 1P9M 1PVH 3L5H 3L5I 3L5J
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activates  activator  ameliorate  attenuate  autoimmune  cd25lowcd44lowcd62lhigh  cd4  coculture  enhance  fate  h3k27me3  h3k4me3  immunomodulatory  immunoregulatory  inhibit  interferon  leading  manifestations  mesenchymal  msc  mscs  promoters  reciprocal  rorgammat  stat1  stat3  suppressors  th17  transducer 
bioinformatics  bmp2  calm1  cnaq  csf2rb  csf3  expressions  fifteen  gria2  il10ra  il10rb  il11ra  il3ra  lifr  lymphatic  microarrays  myl9  mylk  myosin  nonsmokers  nsclc  paraneoplastic  pathohistological  plcb4  ppp2ca  rac3  rock2  thbs1  verify 
Tagcloud (Difference) ?
activates  activator  ameliorate  attenuate  autoimmune  cd25lowcd44lowcd62lhigh  cd4  coculture  enhance  fate  h3k27me3  h3k4me3  immunomodulatory  immunoregulatory  inhibit  interferon  leading  manifestations  mesenchymal  msc  mscs  promoters  reciprocal  rorgammat  stat1  stat3  suppressors  th17  transducer 
bioinformatics  bmp2  calm1  cnaq  csf2rb  csf3  expressions  fifteen  gria2  il10ra  il10rb  il11ra  il3ra  lifr  lymphatic  microarrays  myl9  mylk  myosin  nonsmokers  nsclc  paraneoplastic  pathohistological  plcb4  ppp2ca  rac3  rock2  thbs1  verify 
Tagcloud (Intersection) ?