PDPK1 and MTOR

  • Number of citations of the paper that reports this interaction (PMID 11438723)
  • 10
  • Data Source:
  • HPRD (in vitro)

PDPK1

MTOR

Gene Name 3-phosphoinositide dependent protein kinase 1 mechanistic target of rapamycin (serine/threonine kinase)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 58 interactors: AKT1 AKT2 AKT3 AKTIP APP BLMH C2orf44 CARD11 CDAN1 DDIT4 FAM213B GIT1 HSP90AA1 ILK IRS1 ITGB3 KATNBL1 LUC7L2 MAPK8 MTOR PAK1 PEA15 PHAX PKN1 PKN2 PNO1 POLDIP2 PRKACA PRKCB PRKCD PRKCE PRKCI PRKCZ PRSS23 PTK2B PXN RALGDS RPS6KA1 RPS6KA3 RPS6KB1 RPS6KB2 SBF1 SGK1 SGK2 SGK3 SLC9A3R2 SMARCB1 SOCS3 SRC SRPK1 STRAP TCAP XPO7 XRCC6 YWHAH YWHAQ ZC3HC1 ZNF133 42 interactors: AKT1 AKT1S1 AMBRA1 BCL2L1 C7orf25 CDC37 CFP CLIP1 EIF3F EIF4EBP1 EIF4EBP2 FKBP1A FKBP8 GPHN GSK3B IRS1 MAF1 MLST8 PA2G4 PDPK1 PLD2 PPP2R2A PREX1 PRKAA1 PRKCA PRR5L RHEB RHEBL1 RICTOR RPS6KA1 RPS6KB1 RPS6KB2 RPTOR RRAGB RRAGD SEPT2 STAT3 TELO2 TERT TRAF6 UBQLN1 YWHAQ
Entrez ID 5170 2475
HPRD ID 05556 03134
Ensembl ID ENSG00000140992 ENSG00000198793
Uniprot IDs E9PER6 O15530 B4DZD5 P42345
PDB IDs 1H1W 1OKY 1OKZ 1UU3 1UU7 1UU8 1UU9 1UVR 1W1D 1W1G 1W1H 1Z5M 2BIY 2PE0 2PE1 2PE2 2R7B 2VKI 2XCH 2XCK 3H9O 3HRC 3HRF 3ION 3IOP 3NAX 3NAY 3NUN 3NUS 3NUU 3NUY 3ORX 3ORZ 3OTU 3PWY 3QC4 3QCQ 3QCS 3QCX 3QCY 3QD0 3QD3 3QD4 3RCJ 3RWP 3RWQ 3SC1 4A06 4A07 4AW0 4AW1 1AUE 1FAP 1NSG 2FAP 2GAQ 2NPU 2RSE 3FAP 4DRH 4DRI 4DRJ 4FAP 4JSN 4JSP 4JSV 4JSX 4JT5 4JT6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amplified  bcl2l1  caspase  caspases  executioner  ikbkb  kinome  mb231  mb468  mesenchymal  nodes  nonkinases  phosphatases  phosphatome  r1  r2  regulators  representing  screens  sensitivities  sensitizes  sineg  sirna  skbr3  src  subset  t47d  tnbc  trail 
aib  aminoisobutyric  ars  arsenite  carrier  hormonal  hs  hyperthermic  instigate  involve  k2  km  l6  map  mapkap  maximally  metabolisable  p42  p44  phosphoinositide  pi3k  rapamycin  sapk2  sb  stresses  transport  transporter  vmax  whilst  wortmannin 
Tagcloud (Difference) ?
amplified  bcl2l1  caspase  caspases  executioner  ikbkb  kinome  mb231  mb468  mesenchymal  nodes  nonkinases  phosphatases  phosphatome  r1  r2  regulators  representing  screens  sensitivities  sensitizes  sineg  sirna  skbr3  src  subset  t47d  tnbc  trail 
aib  aminoisobutyric  ars  arsenite  carrier  hormonal  hs  hyperthermic  instigate  involve  k2  km  l6  map  mapkap  maximally  metabolisable  p42  p44  phosphoinositide  pi3k  rapamycin  sapk2  sb  stresses  transport  transporter  vmax  whilst  wortmannin 
Tagcloud (Intersection) ?