SOCS3 and IL2RB

  • Number of citations of the paper that reports this interaction (PMID 10373548)
  • 38

SOCS3

IL2RB

Gene Name suppressor of cytokine signaling 3 interleukin 2 receptor, beta
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood trace element (Se levels) ( 23720494)
Protein-Protein Interactions 48 interactors: ACADVL APP BCL10 BIK CSF1R CSF3R CSNK1E CUEDC2 CXCR4 EGFR EPOR GFRA1 GHR HIVEP1 IGF1R IL12RB2 IL2RB IL6ST INSR IRS1 IRS2 JAK1 JAK2 JAK3 KIAA1958 LEPR MAP1S MAPK11 MAPK6 NME4 PDPK1 PIN1 PPP3CB PRLR PTK2 PTPN11 RASA1 RBMX RNF31 RPL7A SOCS2 TCEB1 TCEB2 TES TFDP1 TFR2 TXNDC11 YES1 27 interactors: CISH EIF3B FYN GNB2L1 GRB2 HGS IL15 IL15RA IL2 IL2RA IL2RG JAK1 JAK3 LCK LYN PIK3R1 PTPN6 RAF1 SHB SHC1 SOCS1 SOCS3 STAT1 STAT3 STAT5A STAT5B SYK
Entrez ID 9021 3560
HPRD ID 05006 00896
Ensembl ID ENSG00000184557 ENSG00000100385
Uniprot IDs O14543 Q6FI39 P14784
PDB IDs 1ILM 1ILN 2B5I 2ERJ 3QAZ 4GS7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activates  activator  ameliorate  attenuate  autoimmune  cd25lowcd44lowcd62lhigh  cd4  coculture  enhance  fate  h3k27me3  h3k4me3  immunomodulatory  immunoregulatory  inhibit  interferon  leading  manifestations  mesenchymal  msc  mscs  promoters  reciprocal  rorgammat  stat1  stat3  suppressors  th17  transducer 
attenuation  autocrine  coculture  coexpression  conundrum  defining  engagement  explanation  favorable  heterotrimer  il15  il15ra  il2rg  infiltrations  jak1  leucocyte  mechanistic  offer  overexpress  paracrine  paradoxical  pras40  rnai  stat2  stroma  subsets  tnbc  unlike 
Tagcloud (Difference) ?
activates  activator  ameliorate  attenuate  autoimmune  cd25lowcd44lowcd62lhigh  cd4  enhance  fate  h3k27me3  h3k4me3  immunomodulatory  immunoregulatory  inhibit  interferon  leading  manifestations  mesenchymal  msc  mscs  promoters  reciprocal  rorgammat  stat1  stat3  suppressors  th17  transducer 
attenuation  autocrine  coexpression  conundrum  defining  engagement  explanation  favorable  heterotrimer  il15  il15ra  il2rg  infiltrations  jak1  leucocyte  mechanistic  offer  overexpress  paracrine  paradoxical  pras40  rnai  stat2  stroma  subsets  tnbc  unlike 
Tagcloud (Intersection) ?
coculture