PDPK1 and MAPK8

  • Number of citations of the paper that reports this interaction (PMID 10357815)
  • 103

PDPK1

MAPK8

Gene Name 3-phosphoinositide dependent protein kinase 1 mitogen-activated protein kinase 8
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 58 interactors: AKT1 AKT2 AKT3 AKTIP APP BLMH C2orf44 CARD11 CDAN1 DDIT4 FAM213B GIT1 HSP90AA1 ILK IRS1 ITGB3 KATNBL1 LUC7L2 MAPK8 MTOR PAK1 PEA15 PHAX PKN1 PKN2 PNO1 POLDIP2 PRKACA PRKCB PRKCD PRKCE PRKCI PRKCZ PRSS23 PTK2B PXN RALGDS RPS6KA1 RPS6KA3 RPS6KB1 RPS6KB2 SBF1 SGK1 SGK2 SGK3 SLC9A3R2 SMARCB1 SOCS3 SRC SRPK1 STRAP TCAP XPO7 XRCC6 YWHAH YWHAQ ZC3HC1 ZNF133 134 interactors: AIMP1 APLP2 APP ATF2 BAD BCL2 BCL2L1 BCL2L11 BMF BMPR2 C11orf57 CAMP CASP3 CBL CCDC88C CDKN1A CDKN2A CDKN2C CEBPA COPS2 CRK CTNNB1 DUSP1 DUSP10 DUSP16 DUSP22 DUSP4 DUSP7 DUSP8 EEF2K ELK1 ELK3 ELK4 EP300 ETV1 FAM193B FZR1 GANAB GARS GEMIN5 GFPT1 GORASP2 GSTP1 GUCY1A3 HDAC9 HIVEP1 HRAS HSD17B4 HSF1 HSF4 HSPA8 ID2 IKBKAP IL27RA IRAK1 IRF3 IRS1 ITCH JDP2 JKAMP JUN JUNB JUND KRT8 MAP1B MAP2K1 MAP2K2 MAP2K4 MAP2K7 MAP3K1 MAP3K2 MAP3K4 MAP3K7 MAPK1 MAPK14 MAPK3 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPKAP1 MAPKBP1 MAPT MKNK2 MYC NCOA3 NFATC3 NFATC4 NFE2 NR3C1 NR4A1 PAX2 PDPK1 PIAS2 PIK3R1 PKMYT1 PNRC1 PPARG PRKD1 PRKDC PXN RAD18 RAF1 RASSF1 RBM15 REL RET RPLP2 RPS6KB1 SCAND1 SCOC SERPINB3 SERPINB4 SH3BP5 SHC1 SIRT1 SMAD2 SMAD3 SNCG SP1 SPAG9 SPI1 SPIB SSU72 STAT3 TFCP2 TNFSF11 TP53 TP73 TRAF6 WDR62 WWOX XRCC6 YWHAZ ZNF219
Entrez ID 5170 5599
HPRD ID 05556 03100
Ensembl ID ENSG00000140992 ENSG00000107643
Uniprot IDs E9PER6 O15530 A1L4K2 P45983 Q308M2
PDB IDs 1H1W 1OKY 1OKZ 1UU3 1UU7 1UU8 1UU9 1UVR 1W1D 1W1G 1W1H 1Z5M 2BIY 2PE0 2PE1 2PE2 2R7B 2VKI 2XCH 2XCK 3H9O 3HRC 3HRF 3ION 3IOP 3NAX 3NAY 3NUN 3NUS 3NUU 3NUY 3ORX 3ORZ 3OTU 3PWY 3QC4 3QCQ 3QCS 3QCX 3QCY 3QD0 3QD3 3QD4 3RCJ 3RWP 3RWQ 3SC1 4A06 4A07 4AW0 4AW1 1UKH 1UKI 2G01 2GMX 2H96 2NO3 2XRW 2XS0 3ELJ 3O17 3O2M 3PZE 3V3V 3VUD 3VUG 3VUH 3VUI 3VUK 3VUL 3VUM 4AWI 4E73 4G1W 4L7F
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amplified  bcl2l1  caspase  caspases  executioner  ikbkb  kinome  mb231  mb468  mesenchymal  nodes  nonkinases  phosphatases  phosphatome  r1  r2  regulators  representing  screens  sensitivities  sensitizes  sineg  sirna  skbr3  src  subset  t47d  tnbc  trail 
abeta1  autophagic  autophagosomes  autophagy  bcl2  beclin  becn1  buildup  digested  elevation  favor  favoring  flux  hamper  incompletely  jnk1  jnk2  lc3  lysosomal  mapk9  modifying  monomers  neuroblastoma  oligomers  phosphorylating  profound  sk  turn  vacuoles 
Tagcloud (Difference) ?
amplified  bcl2l1  caspase  caspases  executioner  ikbkb  kinome  mb231  mb468  mesenchymal  nodes  nonkinases  phosphatases  phosphatome  r1  r2  regulators  representing  screens  sensitivities  sensitizes  sineg  sirna  skbr3  src  subset  t47d  tnbc  trail 
abeta1  autophagic  autophagosomes  autophagy  bcl2  beclin  becn1  buildup  digested  elevation  favor  favoring  flux  hamper  incompletely  jnk1  jnk2  lc3  lysosomal  mapk9  modifying  monomers  neuroblastoma  oligomers  phosphorylating  profound  sk  turn  vacuoles 
Tagcloud (Intersection) ?