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REPS1 and ITSN2
Number of citations of the paper that reports this interaction (PMID
22558309
)
5
Data Source:
BioGRID
(two hybrid)
REPS1
ITSN2
Gene Name
RALBP1 associated Eps domain containing 1
intersectin 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Coated Pit
Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Calcium Ion Binding
Protein Binding
SH3 Domain Binding
SH3/SH2 Adaptor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Biological Process
Receptor-mediated Endocytosis
Endocytosis
Positive Regulation Of Signal Transduction
Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS
Working memory (
21107309
)
Protein-Protein Interactions
13 interactors:
ATF4
CRK
GRB2
HSF1
ITSN2
PIN1
RAB11FIP2
RALA
RALB
RALBP1
REPS2
TRAPPC2L
WWC2
75 interactors:
AGT
AHDC1
AMPH
ANKRD17
BCCIP
CBL
CCDC88C
CHIC2
CPSF6
DLGAP1
DNM2
DST
EPS15
EPS15L1
ERC1
FASLG
FCHSD1
FCHSD2
FNBP4
GAREML
GOLGA2
GOLGA8A
GOLGB1
GPNMB
HNRNPK
HOOK2
ITPKA
ITSN1
KCTD10
KDM1A
KHDRBS1
KIAA1549
KXD1
LARP6
LSM8
LTBP4
LUC7L3
MAP4K3
MBNL1
MEGF10
NBR1
NR2C2
PDCD6IP
PDE4DIP
PIK3AP1
PIK3C2B
PSEN1
PTN
RABEP1
RAD9A
RBMX
REPS1
RNF20
ROCK1
RUFY1
SEMA6A
SH3GL1
SH3KBP1
SNAP29
SOS1
SOS2
STX4
SYN1
SYNJ2
TACC1
TBL3
TMF1
TRIO
WAS
WASF2
WASL
WIPF1
WIPF2
YLPM1
YTHDF1
Entrez ID
85021
50618
HPRD ID
09687
09193
Ensembl ID
ENSG00000135597
ENSG00000198399
Uniprot IDs
J3KP76
Q96D71
A6H8W8
Q9NZM3
PDB IDs
1J3T
1UDL
1UE9
1UFF
1UHF
3GF9
3JZY
Enriched GO Terms of Interacting Partners
?
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Rho GTPase Activity
Response To Organic Substance
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Organic Substance
Regulation Of Rho Protein Signal Transduction
Vesicle-mediated Transport
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Catalytic Activity
Positive Regulation Of Metabolic Process
Regulation Of Ras GTPase Activity
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Transferase Activity
Ras Protein Signal Transduction
Cellular Response To Growth Factor Stimulus
Response To External Stimulus
Response To Growth Factor
Small GTPase Mediated Signal Transduction
Positive Regulation Of Rho GTPase Activity
Cellular Response To Stimulus
Regulation Of Ras Protein Signal Transduction
Regulation Of Phosphorylation
Positive Regulation Of Protein Phosphorylation
Regulation Of Small GTPase Mediated Signal Transduction
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Exocyst Assembly
Signaling
Regulation Of GTPase Activity
Cell Communication
Regulation Of Phosphorus Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Phosphorylation
Regulation Of Exocyst Localization
Positive Regulation Of Autophagic Vacuole Assembly
Positive Regulation Of Vacuole Organization
Positive Regulation Of Protein Modification Process
Regulation Of Organelle Organization
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Ras GTPase Activity
Cytokinesis
Positive Regulation Of Hydrolase Activity
Embryonic Placenta Development
Positive Regulation Of Protein Kinase Activity
Regulation Of Signal Transduction
Regulation Of Protein Phosphorylation
Response To Stimulus
Positive Regulation Of Kinase Activity
Intracellular Signal Transduction
Vesicle-mediated Transport
Endocytosis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Cell Communication
Signaling
Cellular Response To Stimulus
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Cellular Component Assembly
Signal Transduction
Synaptic Vesicle Transport
Enzyme Linked Receptor Protein Signaling Pathway
Actin Filament-based Movement
Cell-cell Signaling
Response To Stimulus
Establishment Of Vesicle Localization
Cell Surface Receptor Signaling Pathway
Vesicle Localization
Organelle Localization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cellular Component Organization
Regulation Of Cellular Process
Negative Regulation Of Membrane Tubulation
Regulation Of Signaling
Protein Complex Assembly
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger
Vesicle Organization
Establishment Of Organelle Localization
Positive Regulation Of Apoptotic Process
Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Immune Response-regulating Signaling Pathway
Positive Regulation Of ERBB Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Cell Death
Transport
Apoptotic Process
Cellular Localization
Regulation Of Cell Death
Positive Regulation Of Intracellular Signal Transduction
Organelle Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Differentiation
Regulation Of Vesicle-mediated Transport
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Establishment Of Localization In Cell
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Difference)
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Intersection)
?