REPS1 and RAB11FIP2

Number of citations of the paper that reports this interaction (PMID 12364336)
25

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro, two hybrid)

		REPS1	RAB11FIP2
Gene Name		RALBP1 associated Eps domain containing 1	RAB11 family interacting protein 2 (class I)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Coated Pit	Nucleoplasm Endosome Plasma Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding	Protein Binding Rab GTPase Binding Protein Kinase Binding Protein Homodimerization Activity
	Biological Process	Receptor-mediated Endocytosis	Renal Water Homeostasis Water Transport Protein Transport Establishment Of Cell Polarity Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Secretory Pathway Transmembrane Transport
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins Aquaporin-mediated transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ATF4 CRK GRB2 HSF1 ITSN2 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2L WWC2	12 interactors: AP2A1 CXCR2 EHD1 ITSN1 MARK2 MYO5B RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAG
Entrez ID		85021	22841
HPRD ID		09687	10548
Ensembl ID		ENSG00000135597	ENSG00000107560
Uniprot IDs		J3KP76 Q96D71	Q3I768 Q7L804
PDB IDs			2GZD 2GZH 2K6S 3TSO 4C4P
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Rho GTPase Activity Response To Organic Substance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Regulation Of Rho Protein Signal Transduction Vesicle-mediated Transport Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Regulation Of Ras GTPase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Transferase Activity Ras Protein Signal Transduction Cellular Response To Growth Factor Stimulus Response To External Stimulus Response To Growth Factor Small GTPase Mediated Signal Transduction Positive Regulation Of Rho GTPase Activity Cellular Response To Stimulus Regulation Of Ras Protein Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Small GTPase Mediated Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Regulation Of Exocyst Assembly Signaling Regulation Of GTPase Activity Cell Communication Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Phosphorylation Regulation Of Exocyst Localization Positive Regulation Of Autophagic Vacuole Assembly Positive Regulation Of Vacuole Organization Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Ras GTPase Activity Cytokinesis Positive Regulation Of Hydrolase Activity Embryonic Placenta Development Positive Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Regulation Of Protein Phosphorylation Response To Stimulus Positive Regulation Of Kinase Activity Intracellular Signal Transduction	Vesicle-mediated Transport Organelle Localization Cellular Localization Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Regulation Of Endocytic Recycling Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Intracellular Protein Transport Endosomal Transport Vesicle Localization Cellular Pigmentation Rab Protein Signal Transduction Endocytosis Protein Localization Establishment Of Organelle Localization Establishment Of Localization In Cell Cellular Protein Localization Pigmentation Regulation Of Vesicle-mediated Transport Chemical Homeostasis Nervous System Development Intracellular Transport Generation Of Neurons Neurogenesis Renal Water Homeostasis Intracellular Signal Transduction Cellular Response To Organic Substance Cell Projection Organization Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Water Transport Fluid Transport Multicellular Organismal Water Homeostasis Homeostatic Process Water Homeostasis Cell Differentiation Positive Regulation Of Cell Migration Neuron Projection Development Negative Regulation Of Neutrophil Apoptotic Process Multivesicular Body Assembly Regulation Of Multivesicular Body Size Positive Regulation Of Cell Motility Exocytosis Positive Regulation Of Cellular Component Movement Receptor-mediated Endocytosis
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