REPS1 and WWC2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		REPS1	WWC2
Gene Name		RALBP1 associated Eps domain containing 1	WW and C2 domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Coated Pit	Cytosol
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding	Kinase Binding Protein Complex Scaffold
	Biological Process	Receptor-mediated Endocytosis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Hippo Signaling Negative Regulation Of Organ Growth
Pathways
Drugs
Diseases
GWAS			Height ( 20881960)
Protein-Protein Interactions		13 interactors: ATF4 CRK GRB2 HSF1 ITSN2 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2L WWC2	2 interactors: REPS1 YWHAQ
Entrez ID		85021	80014
HPRD ID		09687	12529
Ensembl ID		ENSG00000135597	ENSG00000151718
Uniprot IDs		J3KP76 Q96D71	Q6AWC2
PDB IDs
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Rho GTPase Activity Response To Organic Substance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Regulation Of Rho Protein Signal Transduction Vesicle-mediated Transport Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Regulation Of Ras GTPase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Transferase Activity Ras Protein Signal Transduction Cellular Response To Growth Factor Stimulus Response To External Stimulus Response To Growth Factor Small GTPase Mediated Signal Transduction Positive Regulation Of Rho GTPase Activity Cellular Response To Stimulus Regulation Of Ras Protein Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Small GTPase Mediated Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Regulation Of Exocyst Assembly Signaling Regulation Of GTPase Activity Cell Communication Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Phosphorylation Regulation Of Exocyst Localization Positive Regulation Of Autophagic Vacuole Assembly Positive Regulation Of Vacuole Organization Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Ras GTPase Activity Cytokinesis Positive Regulation Of Hydrolase Activity Embryonic Placenta Development Positive Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Regulation Of Protein Phosphorylation Response To Stimulus Positive Regulation Of Kinase Activity Intracellular Signal Transduction	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Substantia Nigra Development
Tagcloud ?			contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwtr1 yap1
Tagcloud (Difference) ?			contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwtr1 yap1
Tagcloud (Intersection) ?