REPS1 and HSF1

Number of citations of the paper that reports this interaction (PMID 12621024)
28

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		REPS1	HSF1
Gene Name		RALBP1 associated Eps domain containing 1	heat shock transcription factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Coated Pit	Nucleoplasm Cytoplasm Cytosol Protein Complex Pronucleus
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Receptor-mediated Endocytosis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Placenta Development Transcription, DNA-templated Protein Phosphorylation Defense Response Female Meiotic Division Spermatogenesis Negative Regulation Of Cell Proliferation Response To Lipopolysaccharide Negative Regulation Of Tumor Necrosis Factor Production Cellular Response To Heat Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Process Involved In Female Pregnancy Regulation Of Spindle Checkpoint Regulation Of Cellular Response To Heat
Pathways			HSF1 activation HSF1-dependent transactivation Attenuation phase Cellular response to heat stress Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ATF4 CRK GRB2 HSF1 ITSN2 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2L WWC2	47 interactors: CAMK2A CDC20 CDK6 CEBPB CHST10 CREBBP CSNK2A1 DAXX DNAJB1 ENO2 FILIP1 FKBP4 FKBP5 GSK3A GTF2A2 GTF2B HSBP1 HSF2 HSPA1A HSPA8 MAPK1 MAPK3 MAPK8 MAPK9 MAPKAPK2 NCOA6 PLK1 PPID PRKDC PTGES3 RALBP1 REPS1 SMARCA4 STAT1 STUB1 SUB1 SUMO1 SUMO3 SYMPK TAF1 TAF7 TAF9 TBP UBE2I XRCC5 XRCC6 YWHAE
Entrez ID		85021	3297
HPRD ID		09687	00778
Ensembl ID		ENSG00000135597	ENSG00000185122
Uniprot IDs		J3KP76 Q96D71	Q00613
PDB IDs			2LDU
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Rho GTPase Activity Response To Organic Substance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Regulation Of Rho Protein Signal Transduction Vesicle-mediated Transport Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Regulation Of Ras GTPase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Transferase Activity Ras Protein Signal Transduction Cellular Response To Growth Factor Stimulus Response To External Stimulus Response To Growth Factor Small GTPase Mediated Signal Transduction Positive Regulation Of Rho GTPase Activity Cellular Response To Stimulus Regulation Of Ras Protein Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Small GTPase Mediated Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Regulation Of Exocyst Assembly Signaling Regulation Of GTPase Activity Cell Communication Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Phosphorylation Regulation Of Exocyst Localization Positive Regulation Of Autophagic Vacuole Assembly Positive Regulation Of Vacuole Organization Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Ras GTPase Activity Cytokinesis Positive Regulation Of Hydrolase Activity Embryonic Placenta Development Positive Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Regulation Of Protein Phosphorylation Response To Stimulus Positive Regulation Of Kinase Activity Intracellular Signal Transduction	Regulation Of Cellular Response To Heat Cellular Response To Heat Cellular Response To Stress Positive Regulation Of Metabolic Process Response To Heat Viral Process Response To Temperature Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Response To Abiotic Stimulus Regulation Of Gene Expression Positive Regulation Of Gene Expression Peptidyl-amino Acid Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Stress Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Chaperone-mediated Protein Folding Positive Regulation Of Transcription, DNA-templated Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Component Organization Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stimulus Negative Regulation Of Transcription, DNA-templated Cellular Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Gene Expression Innate Immune Response Cellular Protein Modification Process Regulation Of Cellular Process Peptidyl-serine Phosphorylation Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Catabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process
Tagcloud ?			atg cloned codon composed consensus contiguous derivatives dnaj element ends extension footprinting gaan heat homologue hse hses hsp40 intron minimal mobility motifs primer race sequences shock supershift transcripts upstream
Tagcloud (Difference) ?			atg cloned codon composed consensus contiguous derivatives dnaj element ends extension footprinting gaan heat homologue hse hses hsp40 intron minimal mobility motifs primer race sequences shock supershift transcripts upstream
Tagcloud (Intersection) ?