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TK1 and UNC119
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
TK1
UNC119
Gene Name
thymidine kinase 1, soluble
unc-119 homolog (C. elegans)
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Spindle Pole
Centrosome
Cytosol
Intercellular Bridge
Spindle Midzone
Molecular Function
Thymidine Kinase Activity
ATP Binding
Zinc Ion Binding
Nucleoside Kinase Activity
Identical Protein Binding
Protein Binding
Lipid Binding
Biological Process
Liver Development
Nucleobase-containing Compound Metabolic Process
Pyrimidine Nucleobase Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Nucleotide Biosynthetic Process
Response To Toxic Substance
Skeletal Muscle Cell Proliferation
Phosphorylation
Response To Nutrient Levels
Pyrimidine Nucleoside Salvage
Small Molecule Metabolic Process
Thymidine Metabolic Process
Response To Copper Ion
Digestive Tract Development
Protein Homotetramerization
Response To Cortisol
Nucleobase-containing Small Molecule Metabolic Process
Fetal Process Involved In Parturition
DNA Biosynthetic Process
Endocytosis
Cytokinesis, Completion Of Separation
Synaptic Transmission
Visual Perception
Phototransduction
Lipoprotein Transport
Positive Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Clathrin-mediated Endocytosis
Negative Regulation Of Caveolin-mediated Endocytosis
Pathways
Pyrimidine salvage reactions
Pyrimidine metabolism
Metabolism of nucleotides
Drugs
Dithioerythritol
Thymidine-5\'-Triphosphate
Diseases
GWAS
Protein-Protein Interactions
159 interactors:
A1BG
A2M
AAMP
ABHD4
ACTB
ACTL6B
ACTR1B
ADAMTS10
ADD1
AGAP1
ALAS1
ALB
APLP1
APP
ARFGAP1
ASNA1
ATG16L2
ATP5B
ATP6V1A
ATXN3
BAG6
C14orf1
C19orf60
CARHSP1
CCDC115
CCDC90B
CDC20
CDK1
CDK4
CDKN1A
CENPB
CHGB
CLEC3B
COL11A2
COL4A2
COL4A5
COPS6
CPNE6
CPSF3L
CRIP2
CRMP1
CSAD
DACT1
DALRD3
DCAF13
DDAH2
DEAF1
DMPK
DOCK7
DRAP1
DUS2
DYNC1I1
EEF1A1
EIF3G
EIF4A2
EIF6
EXT2
EZH2
F13A1
FAF1
FAM20C
FBN3
FGB
FLAD1
FST
FZR1
GAPDH
GDF9
GDI1
GLB1
GPCPD1
HADHB
HERC3
HMGXB3
HSPBAP1
IER3IP1
IGHM
IMMT
INPP5K
ITSN1
JADE1
JMJD1C
KDM6B
KIF21B
KIF5A
KLHL23
KLHL5
KMT2B
LOC148413
LRIF1
MAGEA4
MAST2
MED31
METTL23
MKI67
MPP1
MPPED1
MRFAP1
MRPL37
MSH2
NEUROD2
NGFR
NKIRAS2
NMT2
NRBP1
ODC1
PAAF1
PDE4DIP
PKM
PLD3
PLXNA3
PPP4C
PROC
PSME1
PTPN4
PTPRK
QARS
RBBP4
RBM48
RPA1
RPL13
RPS2
RUVBL1
RXRA
SDF4
SEMA5B
SEPT6
SETDB1
SEZ6L2
SMC5
SNX1
SP110
SULT1A3
SUMO3
TAF1C
TCTEX1D2
THOC3
TIAM2
TLE1
TMSB4X
TP53
TRIM46
TRMT2A
TSC2
TTC38
TUBA1A
TUBB2A
TUBB3
TYK2
UNC119
UPF2
USP4
WDR18
WDR60
WDR73
WIZ
ZBTB16
ZNF431
ZXDC
92 interactors:
AAGAB
ALDH2
AMOT
ANKRD24
ANXA1
ANXA3
ANXA7
ARL15
ARL2
ARL3
ARL4D
ASH2L
BCR
BRIX1
BTBD2
C16orf74
CBX8
CCL18
CD247
CD3E
CD4
CDC42
CDKN1A
CDKN2C
CETN3
CKMT2
CKS2
COX17
CYB561D2
EIF2S2
ERH
FKBPL
FXYD6
FYN
GIPC2
GSTM4
HCK
HLA-DQA1
HMGB1
HSPB3
HSPE1
ID2
IL5RA
ITSN1
KDM1A
LAMA4
LCK
LIG4
LUC7L2
LYN
MAPK10
MAPK8IP2
MPHOSPH6
MRPS12
ORAI2
PAFAH1B3
PAPSS1
PCDHA4
PFN1
PHF10
PIN1
PPA1
PPAP2C
PSMD11
PSMD2
PTPRS
QTRT1
RAP1B
RCC1
RFC5
RGL2
RPA2
RPS6KA5
RUFY3
S100A4
S100A8
SAT1
SEPHS1
SERPINB9
SMN1
SULT1E1
TK1
TP53BP2
TP53I3
TRDMT1
TSC22D1
UBE2B
UBE2I
UBQLN4
ZAK
ZFP64
ZNF24
Entrez ID
7083
9094
HPRD ID
01771
04927
Ensembl ID
ENSG00000167900
ENSG00000109103
Uniprot IDs
P04183
Q13432
PDB IDs
1W4R
1XBT
2ORV
2WVJ
3GQQ
3RBQ
4GOJ
4GOK
Enriched GO Terms of Interacting Partners
?
Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Cellular Protein Metabolic Process
Developmental Process
Anatomical Structure Development
System Development
Regulation Of Cellular Protein Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Multicellular Organismal Development
Cellular Localization
Metabolic Process
Regulation Of Metabolic Process
Organelle Organization
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
Protein Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Catabolic Process
RNA Metabolic Process
Negative Regulation Of Cell Cycle
Posttranscriptional Regulation Of Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Protein Catabolic Process
Negative Regulation Of Cellular Metabolic Process
Cell Differentiation
Platelet Degranulation
Gene Expression
Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle Process
Negative Regulation Of Mitotic Cell Cycle
Cellular Process
Biosynthetic Process
Regulation Of Cell Cycle
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cycle Process
Mitotic Cell Cycle Process
Axon Guidance
Chromatin Organization
Viral Process
Programmed Cell Death
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Chromosome Organization
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Cellular Response To Organic Substance
Mitotic Cell Cycle
Cellular Response To Growth Factor Stimulus
T Cell Costimulation
Regulation Of Catalytic Activity
Response To Stress
Developmental Process
Immune System Process
Regulation Of Defense Response To Virus By Virus
System Development
Anatomical Structure Development
Positive Regulation Of Catalytic Activity
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Response To Stimulus
Immune Response
Regulation Of Apoptotic Process
Defense Response
Cell Cycle
Nervous System Development
Regulation Of Cellular Protein Metabolic Process
Multicellular Organismal Development
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Death
Intracellular Signal Transduction
Regulation Of Protein Metabolic Process
Cellular Response To Stimulus
Antigen Receptor-mediated Signaling Pathway
Positive Regulation Of Immune System Process
Positive Regulation Of Transferase Activity
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of T Cell Activation
Regulation Of Cell Activation
Regulation Of Cell Cycle
Innate Immune Response
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Cell Activation
Regulation Of Lymphocyte Activation
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell-cell Adhesion
Leukocyte Differentiation
T Cell Receptor Signaling Pathway
Regulation Of Cellular Component Organization
Positive Regulation Of Protein Modification Process
Viral Process
Positive Regulation Of Intracellular Signal Transduction
Cell Differentiation
Positive Regulation Of Metabolic Process
Cell Activation
Tagcloud
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
nf1
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
umph2
Tagcloud (Difference)
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
nf1
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
umph2
Tagcloud (Intersection)
?