UNC119 and ANXA3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UNC119	ANXA3
Gene Name		unc-119 homolog (C. elegans)	annexin A3
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Intercellular Bridge Spindle Midzone	Cytoplasm Plasma Membrane Membrane Phagocytic Vesicle Membrane Specific Granule Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Lipid Binding	Calcium Ion Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Calcium-dependent Protein Binding
	Biological Process	Endocytosis Cytokinesis, Completion Of Separation Synaptic Transmission Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis	Phagocytosis Positive Regulation Of Endothelial Cell Migration Defense Response To Bacterium Negative Regulation Of Catalytic Activity Neutrophil Degranulation Positive Regulation Of Angiogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS			Non-albumin protein levels ( 22558069) Rheumatoid arthritis ( 22446963)
Protein-Protein Interactions		92 interactors: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A LAMA4 LCK LIG4 LUC7L2 LYN MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PPA1 PPAP2C PSMD11 PSMD2 PTPRS QTRT1 RAP1B RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TP53BP2 TP53I3 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZAK ZFP64 ZNF24	6 interactors: EMG1 IGSF21 REG3A TP53 UBR1 UNC119
Entrez ID		9094	306
HPRD ID		04927	00111
Ensembl ID		ENSG00000109103	ENSG00000138772
Uniprot IDs		Q13432	P12429
PDB IDs		3GQQ 3RBQ 4GOJ 4GOK	1AII 1AXN
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Regulation Of Catalytic Activity Response To Stress Developmental Process Immune System Process Regulation Of Defense Response To Virus By Virus System Development Anatomical Structure Development Positive Regulation Of Catalytic Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Response To Stimulus Immune Response Regulation Of Apoptotic Process Defense Response Cell Cycle Nervous System Development Regulation Of Cellular Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Intracellular Signal Transduction Regulation Of Protein Metabolic Process Cellular Response To Stimulus Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Transferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of T Cell Activation Regulation Of Cell Activation Regulation Of Cell Cycle Innate Immune Response Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell-cell Adhesion Leukocyte Differentiation T Cell Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Protein Modification Process Viral Process Positive Regulation Of Intracellular Signal Transduction Cell Differentiation Positive Regulation Of Metabolic Process Cell Activation	Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Macromitophagy Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Oligodendrocyte Apoptotic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Negative Regulation Of Keratinocyte Differentiation Regulation Of Caveolin-mediated Endocytosis Mitochondrial DNA Repair Response To Leucine Positive Regulation Of Keratinocyte Proliferation Mitotic Cytokinetic Process Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Oxidative Stress-induced Premature Senescence Response To Light Stimulus Negative Regulation Of Epidermal Cell Differentiation ER Overload Response Negative Regulation Of Macroautophagy Stress-induced Premature Senescence Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of T Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Strand Renaturation Regulation Of Cellular Amino Acid Metabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle Arrest Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Thymocyte Apoptotic Process RRNA Methylation Response To Radiation Replicative Senescence Positive Regulation Of Mitochondrial Membrane Permeability Determination Of Adult Lifespan Positive Regulation Of Lymphocyte Apoptotic Process Circadian Behavior RRNA Modification Mitochondrial DNA Metabolic Process Positive Regulation Of Histone Deacetylation Cell Separation After Cytokinesis Rhythmic Behavior Lipoprotein Transport Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Tagcloud ?			1e 3e 7e accessed adam28 adenocarcinomas cabig cadm1 ccne1 cd24 cdk1 cdkn2a com datasets demonstration ercc1 geo kmplot logrank online opn plot plotted rad51 repositories silico tcga uni www
Tagcloud (Difference) ?			1e 3e 7e accessed adam28 adenocarcinomas cabig cadm1 ccne1 cd24 cdk1 cdkn2a com datasets demonstration ercc1 geo kmplot logrank online opn plot plotted rad51 repositories silico tcga uni www
Tagcloud (Intersection) ?