UNC119 and RCAN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UNC119	RCAN3
Description		unc-119 lipid binding chaperone	RCAN family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Intercellular Bridge Synapse Spindle Midzone	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Lipid Binding	Nucleic Acid Binding RNA Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Phosphatase Binding Troponin I Binding
	Biological Process	Mitotic Cytokinesis Endocytosis Chemical Synaptic Transmission Nervous System Development Visual Perception Phototransduction Protein Transport Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis	Anatomical Structure Morphogenesis Calcium-mediated Signaling
Pathways			SARS-CoV-1 activates/modulates innate immune responses
Drugs
Diseases
GWAS			Male-pattern baldness ( 28196072)
Interacting Genes		104 interacting genes: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CFTR CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A KRTAP1-3 KRTAP9-3 KRTAP9-8 LAMA4 LCK LIG4 LRIF1 LUC7L2 LYN MAP3K20 MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PLPP2 PPA1 PPP3CA PPP3CC PSMD11 PSMD2 PTPRS QTRT1 RAP1B RASSF6 RBPMS2 RCAN3 RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TMEM200A TP53BP2 TP53I3 TP53INP1 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZFP64 ZNF24	5 interacting genes: EPS8 TNNI3 TRIM23 UNC119 ZDHHC17
Entrez ID		9094	11123
HPRD ID		04927	05792
Ensembl ID		ENSG00000109103	ENSG00000117602
Uniprot IDs		K7EN86 Q13432	Q9UKA8
PDB IDs		3GQQ 3RBQ 4GOJ 4GOK 5L7K 6H6A 7UMO 9GKG
Enriched GO Terms of Interacting Partners?		Fc-gamma Receptor Signaling Pathway Fc Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Lymphocyte Activation Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Glutamatergic Synapse Leukocyte Migration Positive Regulation Of Cell Activation Cytosol Enzyme Binding Positive Regulation Of Cell-cell Adhesion Protein Binding T Cell Receptor Binding RAGE Receptor Binding Positive Regulation Of Cell Adhesion Intracellular Signal Transduction Regulation Of Lymphocyte Activation Positive Regulation Of Cell Development Regulation Of Calcium Ion Import Across Plasma Membrane Cytoplasm Nucleus T Cell Activation Positive Regulation Of Monoatomic Ion Transmembrane Transport Gamma-delta T Cell Receptor Complex Lymphocyte Activation Regulation Of Leukocyte Cell-cell Adhesion Calcium-dependent Protein Binding Regulation Of T Cell Activation Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Cellular Developmental Process T Cell Costimulation Positive Regulation Of Leukocyte Differentiation T Cell Receptor Complex Intracellular Signaling Cassette CD8 Receptor Binding Nucleotide Binding Gamma-delta T Cell Activation Negative Regulation Of Cell Development Peptidyl-tyrosine Phosphorylation Regulation Of Mitotic Cell Cycle Phagocytosis Regulation Of Leukocyte Proliferation Response To Gamma Radiation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Schaffer Collateral - CA1 Synapse	Lipoprotein Transport Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Perforant Pathway To Dendrate Granule Cell Synapse Negative Regulation Of Caveolin-mediated Endocytosis Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Cardiac Troponin Complex Troponin C Binding Troponin T Binding Negative Regulation Of Clathrin-dependent Endocytosis Synapse Protein-cysteine S-myristoyltransferase Activity Protein Transport Actin Polymerization-dependent Cell Motility Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Troponin Complex Cardiac Myofibril Regulation Of Caveolin-mediated Endocytosis Protein-cysteine S-stearoyltransferase Activity NMDA Selective Glutamate Receptor Complex Positive Regulation Of Protein Tyrosine Kinase Activity Behavioral Response To Ethanol Stereocilium Bundle Establishment Of Protein Localization Positive Regulation Of Ruffle Assembly Actin Crosslink Formation Stereocilium Tip Exit From Mitosis Negative Regulation Of ATP-dependent Activity Contractile Muscle Fiber Calcium Channel Inhibitor Activity Muscle Filament Sliding Regulation Of Neurotrophin TRK Receptor Signaling Pathway Golgi-associated Vesicle Membrane Actin Binding Actin Filament-based Process Barbed-end Actin Filament Capping Actin-myosin Filament Sliding Regulation Of Clathrin-dependent Endocytosis Protein Palmitoylation Palmitoyltransferase Activity Regulation Of Modification Of Synaptic Structure Protein-cysteine S-palmitoyltransferase Activity
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