UNC119 and RCC1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		UNC119	RCC1
Gene Name		unc-119 homolog (C. elegans)	regulator of chromosome condensation 1
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Intercellular Bridge Spindle Midzone	Nuclear Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	Protein Binding Lipid Binding	Chromatin Binding Ran Guanyl-nucleotide Exchange Factor Activity Protein Binding Nucleosomal DNA Binding Histone Binding
	Biological Process	Endocytosis Cytokinesis, Completion Of Separation Synaptic Transmission Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Viral Process Positive Regulation Of Ran GTPase Activity Spindle Assembly Cell Division
Pathways			HIV Life Cycle Rev-mediated nuclear export of HIV RNA HIV Infection Nuclear import of Rev protein Rev-mediated nuclear export of HIV RNA Host Interactions of HIV factors Interactions of Rev with host cellular proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		92 interactors: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A LAMA4 LCK LIG4 LUC7L2 LYN MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PPA1 PPAP2C PSMD11 PSMD2 PTPRS QTRT1 RAP1B RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TP53BP2 TP53I3 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZAK ZFP64 ZNF24	50 interactors: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 FAF1 FLAD1 GNB2 HADHB HIST1H3A HIST1H4A HIST2H2AA3 HIST2H2AC HIST2H2BE HMGA1 HOXD8 KMT2B KPNA3 KPNA4 KPNB1 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 TLE1 TP53 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		9094	1104
HPRD ID		04927	01559
Ensembl ID		ENSG00000109103	ENSG00000180198
Uniprot IDs		Q13432	P18754 Q5T081
PDB IDs		3GQQ 3RBQ 4GOJ 4GOK	1A12 1I2M
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Regulation Of Catalytic Activity Response To Stress Developmental Process Immune System Process Regulation Of Defense Response To Virus By Virus System Development Anatomical Structure Development Positive Regulation Of Catalytic Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Response To Stimulus Immune Response Regulation Of Apoptotic Process Defense Response Cell Cycle Nervous System Development Regulation Of Cellular Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Intracellular Signal Transduction Regulation Of Protein Metabolic Process Cellular Response To Stimulus Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Transferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of T Cell Activation Regulation Of Cell Activation Regulation Of Cell Cycle Innate Immune Response Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell-cell Adhesion Leukocyte Differentiation T Cell Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Protein Modification Process Viral Process Positive Regulation Of Intracellular Signal Transduction Cell Differentiation Positive Regulation Of Metabolic Process Cell Activation	Protein Localization To Nucleus Protein Import Into Nucleus Nuclear Import Intracellular Transport Of Virus Protein Localization To Organelle Protein Import Nucleocytoplasmic Transport Nuclear Transport Cell Cycle Mitotic Cell Cycle DNA Packaging Cellular Component Assembly Protein Complex Assembly Cell Cycle Process Chromatin Assembly Cellular Localization Cellular Protein Localization Chromatin Organization NLS-bearing Protein Import Into Nucleus Viral Process Protein Localization Ribosomal Small Subunit Export From Nucleus Chromatin Assembly Or Disassembly DNA Conformation Change Cellular Nitrogen Compound Metabolic Process Chromosome Organization Viral Life Cycle Mitotic Cell Cycle Process Cellular Metabolic Process Positive Regulation Of Cell Aging Establishment Of Protein Localization To Organelle Organelle Organization Establishment Of Protein Localization Ribosomal Large Subunit Export From Nucleus Nitrogen Compound Metabolic Process Intracellular Transport Ribosomal Subunit Export From Nucleus DNA Replication-dependent Nucleosome Assembly Protein Targeting Nucleosome Organization DNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process 'de Novo' Posttranslational Protein Folding Cellular Macromolecular Complex Assembly 'de Novo' Protein Folding Base-excision Repair DNA Methylation On Cytosine Protein Transport Protein-DNA Complex Assembly
Tagcloud ?			almost cellulose chromosome column condensation consistently cytoplasm digestion dispersed dnase eluted encode kd located locates maturation mitotic nacl nuclei onset p45 prepared presumably putative regulating regulator released sequential synthetic
Tagcloud (Difference) ?			almost cellulose chromosome column condensation consistently cytoplasm digestion dispersed dnase eluted encode kd located locates maturation mitotic nacl nuclei onset p45 prepared presumably putative regulating regulator released sequential synthetic
Tagcloud (Intersection) ?