UNC119 and GIPC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UNC119	GIPC2
Gene Name		unc-119 homolog (C. elegans)	GIPC PDZ domain containing family, member 2
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Intercellular Bridge Spindle Midzone	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Lipid Binding	Molecular_function
	Biological Process	Endocytosis Cytokinesis, Completion Of Separation Synaptic Transmission Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis	Biological_process
Pathways
Drugs
Diseases
GWAS			Height ( 20881960)
Protein-Protein Interactions		92 interactors: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A LAMA4 LCK LIG4 LUC7L2 LYN MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PPA1 PPAP2C PSMD11 PSMD2 PTPRS QTRT1 RAP1B RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TP53BP2 TP53I3 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZAK ZFP64 ZNF24	7 interactors: FZD3 IGSF21 PTN SETDB1 SP100 UNC119 ZBTB26
Entrez ID		9094	54810
HPRD ID		04927	17040
Ensembl ID		ENSG00000109103
Uniprot IDs		Q13432	Q8TF65
PDB IDs		3GQQ 3RBQ 4GOJ 4GOK	3GGE
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Regulation Of Catalytic Activity Response To Stress Developmental Process Immune System Process Regulation Of Defense Response To Virus By Virus System Development Anatomical Structure Development Positive Regulation Of Catalytic Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Response To Stimulus Immune Response Regulation Of Apoptotic Process Defense Response Cell Cycle Nervous System Development Regulation Of Cellular Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Intracellular Signal Transduction Regulation Of Protein Metabolic Process Cellular Response To Stimulus Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Transferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of T Cell Activation Regulation Of Cell Activation Regulation Of Cell Cycle Innate Immune Response Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell-cell Adhesion Leukocyte Differentiation T Cell Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Protein Modification Process Viral Process Positive Regulation Of Intracellular Signal Transduction Cell Differentiation Positive Regulation Of Metabolic Process Cell Activation	Negative Regulation Of Clathrin-mediated Endocytosis Cell Proliferation In Midbrain Negative Regulation Of Mitotic Cell Cycle, Embryonic Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Fas Signaling Pathway Cytokinesis, Completion Of Separation Regulation Of Mitotic Cell Cycle, Embryonic Negative Regulation Of Protein Export From Nucleus Regulation Of Caveolin-mediated Endocytosis Learning Or Memory Mitotic Cytokinetic Process Negative Regulation Of Execution Phase Of Apoptosis Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Neurological System Process Cognition Histone H3-K9 Trimethylation
Tagcloud ?			adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc1 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 sema4c tgfbetar3 vangl2
Tagcloud (Difference) ?			adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc1 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 sema4c tgfbetar3 vangl2
Tagcloud (Intersection) ?