UNC119 and RGL2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UNC119	RGL2
Gene Name		unc-119 homolog (C. elegans)	ral guanine nucleotide dissociation stimulator-like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Intercellular Bridge Spindle Midzone	Cellular_component Intracellular
	Molecular Function	Protein Binding Lipid Binding	Ras Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Endocytosis Cytokinesis, Completion Of Separation Synaptic Transmission Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis	Ras Protein Signal Transduction Positive Regulation Of Ras GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		92 interactors: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A LAMA4 LCK LIG4 LUC7L2 LYN MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PPA1 PPAP2C PSMD11 PSMD2 PTPRS QTRT1 RAP1B RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TP53BP2 TP53I3 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZAK ZFP64 ZNF24	14 interactors: CCDC90B CRMP1 EEF1G HRAS KAT5 KAT7 KPNA2 KRAS NOTCH2NL NRAS RAC1 RALA RAP1B UNC119
Entrez ID		9094	5863
HPRD ID		04927	03810
Ensembl ID		ENSG00000109103	ENSG00000237441
Uniprot IDs		Q13432	O15211
PDB IDs		3GQQ 3RBQ 4GOJ 4GOK
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Regulation Of Catalytic Activity Response To Stress Developmental Process Immune System Process Regulation Of Defense Response To Virus By Virus System Development Anatomical Structure Development Positive Regulation Of Catalytic Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Response To Stimulus Immune Response Regulation Of Apoptotic Process Defense Response Cell Cycle Nervous System Development Regulation Of Cellular Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Intracellular Signal Transduction Regulation Of Protein Metabolic Process Cellular Response To Stimulus Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Transferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of T Cell Activation Regulation Of Cell Activation Regulation Of Cell Cycle Innate Immune Response Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell-cell Adhesion Leukocyte Differentiation T Cell Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Protein Modification Process Viral Process Positive Regulation Of Intracellular Signal Transduction Cell Differentiation Positive Regulation Of Metabolic Process Cell Activation	Positive Regulation Of Rac Protein Signal Transduction Neurotrophin Signaling Pathway Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Small GTPase Mediated Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Positive Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Transferase Activity Cellular Response To Growth Factor Stimulus Chemotaxis Response To Growth Factor Small GTPase Mediated Signal Transduction Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Synaptic Transmission, GABAergic Regulation Of Rac Protein Signal Transduction Response To External Stimulus Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Axon Guidance Cellular Response To Organic Substance Regulation Of Kinase Activity Blood Coagulation Hemostasis Epithelial Tube Branching Involved In Lung Morphogenesis Response To Radiation Positive Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Neuronal Synaptic Plasticity Visual Learning Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Activation Of MAPKK Activity Lung Morphogenesis Visual Behavior Axonogenesis Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Protein Phosphorylation Fc Receptor Signaling Pathway Wound Healing Actin Cytoskeleton Organization Response To Abiotic Stimulus Associative Learning Positive Regulation Of Cell Projection Organization Response To Organic Substance Neuron Projection Morphogenesis
Tagcloud ?			21d abi3 abscisic aco4 albeit alternating biosynthetic della disparate domesticated dormancy dormant ethylene germinate germinating germination gibberellin hub hy5 imbibed imbibition leafy phenylpropanoid seeds spurge surge temperate temporary transcriptome
Tagcloud (Difference) ?			21d abi3 abscisic aco4 albeit alternating biosynthetic della disparate domesticated dormancy dormant ethylene germinate germinating germination gibberellin hub hy5 imbibed imbibition leafy phenylpropanoid seeds spurge surge temperate temporary transcriptome
Tagcloud (Intersection) ?