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TBL1X and H3C14
Number of citations of the paper that reports this interaction (PubMedID
12628926
)
40
Data Source:
BioGRID
(pull down)
TBL1X
H3C14
Description
transducin beta like 1 X-linked
H3 clustered histone 14
Image
GO Annotations
Cellular Component
Histone Deacetylase Complex
Nucleus
Nucleoplasm
Transcription Repressor Complex
Mitotic Spindle
Chromatin
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Chromosome
Extracellular Exosome
Molecular Function
Transcription Cis-regulatory Region Binding
Transcription Corepressor Activity
Protein Binding
Histone Binding
Identical Protein Binding
DNA Binding
Chromatin Binding
Protein Binding
Structural Constituent Of Chromatin
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Proteolysis
Sensory Perception Of Sound
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Protein Stabilization
Positive Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Nucleosome Assembly
Gene Expression
Pathways
BMAL1:CLOCK,NPAS2 activates circadian expression
PPARA activates gene expression
PPARA activates gene expression
NOTCH1 Intracellular Domain Regulates Transcription
Transcriptional activation of mitochondrial biogenesis
Activation of gene expression by SREBF (SREBP)
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HDACs deacetylate histones
Notch-HLH transcription pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by PPARalpha
Loss of MECP2 binding ability to the NCoR/SMRT complex
Regulation of MECP2 expression and activity
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
HCMV Early Events
Cytoprotection by HMOX1
Heme signaling
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Expression of BMAL (ARNTL), CLOCK, and NPAS2
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
Interleukin-7 signaling
Interleukin-7 signaling
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
HDACs deacetylate histones
PKMTs methylate histone lysines
HDMs demethylate histones
HATs acetylate histones
HATs acetylate histones
RMTs methylate histone arginines
Chromatin modifying enzymes
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Assembly of the ORC complex at the origin of replication
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Defective pyroptosis
Negative Regulation of CDH1 Gene Transcription
Amyloid fiber formation
Chromatin modifications during the maternal to zygotic transition (MZT)
Factors involved in megakaryocyte development and platelet production
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Refractive error (
32231278
)
Interacting Genes
31 interacting genes:
ARL2
ARL3
CDC34
CORO2A
CTNNB1
DDB1
DLX3
DNAJB4
FOXK2
GPS2
H2AC18
H2BC21
H3C14
H4C1
H4C14
HDAC3
HP
HR
KHDRBS1
MECP2
NCOR1
NCOR2
SKP1
TAB2
TBL1XR1
TERF1
THRA
THRB
TINF2
UBE2D1
UBE2I
66 interacting genes:
ARID4A
ATRX
AURKB
BIRC5
BRD1
BRD4
BRD7
BRPF1
CBX2
CBX4
CBX6
CBX7
CBX8
CDCA8
CDK8
CHUK
DDB2
DNAJC9
DNMT3L
EHMT2
ELP3
EP300
HDGFL2
INCENP
ING1
JADE1
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM2A
KDM3A
KDM4C
KDM6A
KMT2A
KMT2B
KMT2C
KMT2D
MSL2
NAP1L4
NASP
NCOA6
NRDC
NSD2
PHF21A
PIM1
PKN1
PRMT6
PTMA
PWWP3A
RBBP4
RBBP5
RERE
RNF20
RNF4
RPS6KA5
SETD1A
SETD1B
SETD7
SMARCA4
SMYD2
STAT6
TBL1X
UHRF1
VRK1
Entrez ID
6907
126961
HPRD ID
02183
11822
Ensembl ID
ENSG00000101849
ENSG00000203811
Uniprot IDs
O60907
Q71DI3
PDB IDs
2XTC
2XTD
2XTE
2IIJ
2X4W
2X4X
2X4Y
3AV1
3DB3
3MO8
3QO2
3R93
4MZF
4MZG
4MZH
4OUC
5B0Y
5B0Z
5B40
5BO0
5CIU
5VAC
6ACE
6FML
6T79
6T7A
6T7B
6T7C
6T7D
6X59
6X5A
6XJD
6Y5D
6Y5E
7BQZ
7BU9
7JO9
7JOA
7JZV
7PET
7PEU
7PEV
7PEW
7PEX
7PEY
7PEZ
7PF0
7PF2
7PF3
7PF4
7PF5
7PF6
7PFA
7PFC
7PFD
7PFE
7PFF
7PFT
7PFU
7PFV
7PFW
7PFX
7TAN
7U50
7U51
7U52
7U53
7UV9
7UVA
7XCR
7XCT
7XD0
7YRD
8AAG
8ATF
8AV6
8GRQ
8HQY
8HR1
8JLB
8JLD
8OL1
8VMJ
8VMN
8VO0
8VOB
8VWS
8VWT
8VWU
8VWV
8X7I
8X7J
8X7K
9DWF
9DWG
9DWH
9DWI
9DWJ
9DWK
9DWL
9DWM
9GMK
9GMR
9IPU
Enriched GO Terms of Interacting Partners
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Nucleoplasm
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
DNA Binding
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Transcription Repressor Complex
Negative Regulation Of Macromolecule Metabolic Process
Chromatin Organization
Nucleus
Transcription Corepressor Activity
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Structural Constituent Of Chromatin
Regulation Of Nucleobase-containing Compound Metabolic Process
Histone Deacetylase Complex
Nucleosome
Regulation Of Primary Metabolic Process
Female Courtship Behavior
Regulation Of Metabolic Process
Cellular Component Assembly
Regulation Of Macromolecule Biosynthetic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Thyroid Hormone Receptor Signaling Pathway
Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway
Maintenance Of Protein Location In Nucleus
Chromatin
Lung Epithelial Cell Differentiation
Lung Cell Differentiation
Chromosome, Telomeric Region
Regulation Of Macromolecule Metabolic Process
Chromatin DNA Binding
Chromatin Binding
Chromosome
Regulation Of RNA Metabolic Process
Thyroid Hormone Binding
Negative Regulation Of JNK Cascade
Shelterin Complex
Regulation Of Thyroid Hormone Receptor Signaling Pathway
Nucleosome Assembly
Nuclear Body
Negative Regulation Of Intracellular Signal Transduction
Ubiquitin-dependent Protein Catabolic Process
Maintenance Of Protein Localization In Organelle
Modification-dependent Protein Catabolic Process
Chromatin Organization
Chromatin Remodeling
Nucleoplasm
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Nucleus
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Chromatin Binding
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Metabolic Process
Chromosome
Positive Regulation Of Biosynthetic Process
Histone Binding
Histone Methyltransferase Complex
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Histone H3K4 Monomethyltransferase Activity
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Histone H3K4 Trimethyltransferase Activity
Transcription Coactivator Activity
Positive Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Chromatin
Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Transferase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Epigenetic Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Histone H3 Methyltransferase Activity
Negative Regulation Of Biosynthetic Process
P53 Binding
Regulation Of Metaphase Plate Congression
Histone H3K4 Methyltransferase Activity
Methylation
Methyltransferase Activity
Acetyltransferase Activity
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