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HIST2H3C and NASP
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
HIST2H3C
NASP
Gene Name
histone cluster 2, H3c
nuclear autoantigenic sperm protein (histone-binding)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Extracellular Vesicular Exosome
Nuclear Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Protein Complex
Molecular Function
DNA Binding
Protein Binding
Protein Heterodimerization Activity
Histone Binding
Hsp90 Protein Binding
Biological Process
Chromatin Silencing At RDNA
Blood Coagulation
Gene Expression
DNA Methylation On Cytosine
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Blastocyst Development
DNA Replication
DNA Replication-dependent Nucleosome Assembly
DNA Replication-independent Nucleosome Assembly
Cell Cycle
Cell Proliferation
Protein Transport
Histone Exchange
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
PKMTs methylate histone lysines
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
HDMs demethylate histones
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
Factors involved in megakaryocyte development and platelet production
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions
61 interactors:
ARID4A
ATRX
AURKB
BIRC5
BRD1
BRD4
BRD7
BRPF1
CDCA8
CDK8
CHUK
COPRS
DDB2
DNMT3L
EHMT2
ELP3
EP300
HDGFRP2
INCENP
ING1
JADE1
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM2A
KDM3A
KDM4C
KDM6A
KMT2A
KMT2B
KMT2C
KMT2D
MSL2
MUM1
NAP1L4
NASP
NCOA6
NRD1
PHF21A
PIM1
PKN1
PRMT6
PTMA
RBBP4
RBBP5
RERE
RNF20
RNF4
RPS6KA5
SETD1A
SETD1B
SETD7
SMARCA4
SMYD2
STAT6
TBL1X
UHRF1
VRK1
WHSC1
14 interactors:
H3F3B
H3F3C
HDAC6
HIST1H1A
HIST1H1C
HIST1H3G
HIST1H3H
HIST1H4A
HIST2H3C
LUC7L2
PTK2
TERF2
TERF2IP
ULK2
Entrez ID
126961
4678
HPRD ID
11822
04423
Ensembl ID
ENSG00000132780
Uniprot IDs
Q71DI3
P49321
Q5T626
PDB IDs
2IIJ
2X4W
2X4X
2X4Y
3AV1
3DB3
3MO8
3QO2
3R93
Enriched GO Terms of Interacting Partners
?
Chromatin Modification
Chromatin Organization
Histone Modification
Chromosome Organization
Peptidyl-lysine Modification
Organelle Organization
Peptidyl-amino Acid Modification
Transcription, DNA-templated
RNA Biosynthetic Process
Cellular Protein Modification Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
RNA Metabolic Process
Histone Methylation
Gene Expression
Peptidyl-lysine Methylation
Methylation
Cellular Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Protein Methylation
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Histone Lysine Methylation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Protein Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Histone Acetylation
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Protein Acetylation
Regulation Of Transcription From RNA Polymerase II Promoter
Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Protein Metabolic Process
Histone H3 Acetylation
Positive Regulation Of Cellular Biosynthetic Process
Histone H3-K4 Methylation
Regulation Of Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
DNA Methylation On Cytosine
Chromatin Silencing At RDNA
Chromatin Silencing
Nucleosome Assembly
Chromatin Assembly
Nucleosome Organization
Chromatin Assembly Or Disassembly
DNA Methylation
Protein-DNA Complex Assembly
Negative Regulation Of Gene Expression, Epigenetic
DNA Packaging
Cellular Macromolecular Complex Assembly
Chromosome Organization
DNA Modification
Regulation Of Gene Expression, Epigenetic
Chromatin Organization
Gene Silencing
DNA Conformation Change
Cellular Component Assembly
DNA Replication-dependent Nucleosome Assembly
Organelle Organization
Protein Complex Assembly
DNA Metabolic Process
Protection From Non-homologous End Joining At Telomere
Telomere Capping
Methylation
Blood Coagulation
Hemostasis
Protein Localization To Chromosome, Telomeric Region
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Telomere Maintenance
Regulation Of Body Fluid Levels
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Wound Healing
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Response To Stress
Response To Wounding
Regulation Of Cellular Component Organization
Regulation Of Telomere Maintenance
Negative Regulation Of Gene Expression
RNA-dependent DNA Replication
Regulation Of Gene Silencing
Protein Localization To Chromosome
Telomere Maintenance Via Telomere Lengthening
DNA Replication-independent Nucleosome Assembly
Gene Expression
Tagcloud
?
1990s
aerial
barkley
canada
concentrated
discharge
discharges
effort
entrance
fit
fuca
grid
harbours
inform
inputs
juan
oily
operations
output
pacific
scenarios
shore
sound
strait
surveillance
tourist
trying
vessel
zeros
Tagcloud (Difference)
?
1990s
aerial
barkley
canada
concentrated
discharge
discharges
effort
entrance
fit
fuca
grid
harbours
inform
inputs
juan
oily
operations
output
pacific
scenarios
shore
sound
strait
surveillance
tourist
trying
vessel
zeros
Tagcloud (Intersection)
?