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HIST2H3C and JADE1
Number of citations of the paper that reports this interaction (PMID
19187766
)
32
Data Source:
BioGRID
(pull down)
HIST2H3C
JADE1
Gene Name
histone cluster 2, H3c
jade family PHD finger 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Extracellular Vesicular Exosome
Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Cytoplasm
Plasma Membrane
Intercellular Bridge
Molecular Function
DNA Binding
Protein Binding
Protein Heterodimerization Activity
RNA Polymerase II Transcription Coactivator Activity
Protein Binding
Zinc Ion Binding
Biological Process
Chromatin Silencing At RDNA
Blood Coagulation
Gene Expression
DNA Methylation On Cytosine
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Chromatin Organization
Transcription, DNA-templated
Apoptotic Process
Response To Stress
Negative Regulation Of Cell Growth
Histone H3 Acetylation
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Histone H4-K12 Acetylation
Histone H4-K16 Acetylation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
PKMTs methylate histone lysines
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
HDMs demethylate histones
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
Factors involved in megakaryocyte development and platelet production
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Chromatin modifying enzymes
Chromatin organization
HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions
61 interactors:
ARID4A
ATRX
AURKB
BIRC5
BRD1
BRD4
BRD7
BRPF1
CDCA8
CDK8
CHUK
COPRS
DDB2
DNMT3L
EHMT2
ELP3
EP300
HDGFRP2
INCENP
ING1
JADE1
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM2A
KDM3A
KDM4C
KDM6A
KMT2A
KMT2B
KMT2C
KMT2D
MSL2
MUM1
NAP1L4
NASP
NCOA6
NRD1
PHF21A
PIM1
PKN1
PRMT6
PTMA
RBBP4
RBBP5
RERE
RNF20
RNF4
RPS6KA5
SETD1A
SETD1B
SETD7
SMARCA4
SMYD2
STAT6
TBL1X
UHRF1
VRK1
WHSC1
16 interactors:
AKT1
CCDC94
CTNNB1
HIST2H3C
HMOX2
ING4
KAT7
MEAF6
PFDN1
SEPT8
SMN1
TK1
UBE2E1
UBE2H
UBE3A
VHL
Entrez ID
126961
79960
HPRD ID
11822
10151
Ensembl ID
ENSG00000077684
Uniprot IDs
Q71DI3
Q6IE81
PDB IDs
2IIJ
2X4W
2X4X
2X4Y
3AV1
3DB3
3MO8
3QO2
3R93
Enriched GO Terms of Interacting Partners
?
Chromatin Modification
Chromatin Organization
Histone Modification
Chromosome Organization
Peptidyl-lysine Modification
Organelle Organization
Peptidyl-amino Acid Modification
Transcription, DNA-templated
RNA Biosynthetic Process
Cellular Protein Modification Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
RNA Metabolic Process
Histone Methylation
Gene Expression
Peptidyl-lysine Methylation
Methylation
Cellular Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Protein Methylation
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Histone Lysine Methylation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Protein Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Histone Acetylation
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Protein Acetylation
Regulation Of Transcription From RNA Polymerase II Promoter
Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Protein Metabolic Process
Histone H3 Acetylation
Positive Regulation Of Cellular Biosynthetic Process
Histone H3-K4 Methylation
Regulation Of Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Histone H4-K12 Acetylation
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Protein K48-linked Ubiquitination
Histone H3 Acetylation
Histone H4 Acetylation
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Histone Acetylation
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Cellular Metabolic Process
Protein Acetylation
Histone Modification
Cell Cycle
Protein Polyubiquitination
Gland Development
Cellular Protein Modification Process
Androgen Receptor Signaling Pathway
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Cellular Protein Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Myelination
Chromatin Modification
Regulation Of RNA Metabolic Process
Protein Catabolic Process
Peptidyl-lysine Modification
Sperm Entry
Glycogen Cell Differentiation Involved In Embryonic Placenta Development
Fetal Process Involved In Parturition
Response To Hypoxia
Prostate Gland Development
Chromatin Organization
Cellular Response To Mechanical Stimulus
Regulation Of Gene Expression
Intracellular Steroid Hormone Receptor Signaling Pathway
Execution Phase Of Apoptosis
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Chromosome Segregation
Multicellular Organismal Reproductive Process
Negative Regulation Of Mitotic Cell Cycle, Embryonic
Skeletal Muscle Cell Proliferation
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Schwann Cell Proliferation
Cellular Response To Insulin-like Growth Factor Stimulus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Tagcloud
?
acetylates
acetylation
bulk
ceased
demonstrating
diminished
epithelial
h4
hbo1
histones
implicate
injured
isoforms
kidneys
lysine
lysines
marks
mcm7
nuclei
reached
recovered
recovery
regenerating
reperfusion
replication
returned
tubular
Tagcloud (Difference)
?
acetylates
acetylation
bulk
ceased
demonstrating
diminished
epithelial
h4
hbo1
histones
implicate
injured
isoforms
kidneys
lysine
lysines
marks
mcm7
nuclei
reached
recovered
recovery
regenerating
reperfusion
replication
returned
tubular
Tagcloud (Intersection)
?