TBCD and SMAD9

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		TBCD	SMAD9
Gene Name		tubulin folding cofactor D	SMAD family member 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Adherens Junction Tight Junction Lateral Plasma Membrane	Intracellular Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding Beta-tubulin Binding Chaperone Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity Metal Ion Binding
	Biological Process	Protein Folding Post-chaperonin Tubulin Folding Pathway Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Microtubule Polymerization Adherens Junction Assembly Positive Regulation Of GTPase Activity Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Transmembrane Transport Tight Junction Assembly	Ureteric Bud Development Response To Hypoxia Mullerian Duct Regression Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway BMP Signaling Pathway Midbrain Development Hindbrain Development Intracellular Signal Transduction Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Cartilage Development Bone Development Cellular Response To Organic Cyclic Compound
Pathways		Protein folding Post-chaperonin tubulin folding pathway Orphan transporters	Signaling by BMP
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ACD APP ARL2 DEXI POLR2I POT1 SMAD9 TBCE TERF1 TUBB XRCC6	117 interactors: ABTB1 ACTB ACVR1 AFF1 AP2A1 ARHGAP9 ARID1B ARNT ASB2 ASH2L BAZ1A BTG2 C10orf2 CAMSAP1 CEP135 CHPF CLPB CPXM2 CSH1 CSH2 CTR9 CXXC5 CYP11A1 DIAPH3 DKK1 DNAJA3 DNAJC7 DST DSTN E4F1 EIF3C EIF3E EIF3F ERVV-1 EVC2 EXPH5 FLI1 FN1 FTL GRN HEY1 HEYL HUWE1 KDM1A KDM6A KIAA0226 KMT2D LEMD3 LMO4 LNPEP LRP5 MAN1A2 MAN1C1 MAN2B1 MBD1 MCM3AP METAP1 MGAT1 MTMR10 MTMR11 NAGK OTUB1 PABPC4 PAPPA PELP1 PHKA2 PIR PKP2 PLEC PNPLA2 PPARD PPP2R5E PRMT6 PSAP PSMD8 QARS RANBP9 RFX1 RMND5A RNF123 RRBP1 SECISBP2 SF3B1 SIL1 SMAD2 SMAD3 SMAD4 SMG1 SNRNP70 SPTBN1 STAG1 SVEP1 TBCD TERF1 TINAGL1 TMEM57 TOB1 TRIM29 TRIP12 TTC37 UBA6 UBE3A UBQLN1 UBQLN4 UNC45A VCPIP1 VPS8 XAB2 YWHAQ ZEB2 ZNF484 ZNF557 ZNF587 ZNF587B ZNF592 ZNF83 ZSCAN4
Entrez ID		6904	4093
HPRD ID		05227	04484
Ensembl ID		ENSG00000141556	ENSG00000120693
Uniprot IDs		J3KR97 Q9BTW9	O15198
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Telomere Assembly Telomere Capping Positive Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cellular Biosynthetic Process Regulation Of DNA Replication Positive Regulation Of DNA Biosynthetic Process DNA Metabolic Process RNA-dependent DNA Replication Cellular Component Assembly Negative Regulation Of DNA Biosynthetic Process Organelle Organization Regulation Of Microtubule Polymerization Regulation Of Chromosome Organization Telomere Maintenance Via Telomere Lengthening Homeostatic Process Microtubule-based Process Negative Regulation Of Catalytic Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Replication Regulation Of Organelle Organization Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Maintenance Of Transcriptional Fidelity During DNA-templated Transcription Elongation From RNA Polymerase II Promoter DNA Duplex Unwinding Response To Stimulus DNA Geometric Change Positive Regulation Of Organelle Organization Chromosome Organization Nucleobase-containing Compound Metabolic Process Microtubule Cytoskeleton Organization Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process	Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Gene Expression Cellular Metabolic Process Transcription, DNA-templated Biosynthetic Process RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Process Cellular Protein Metabolic Process Protein Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Gastrulation Anterior/posterior Pattern Specification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Developmental Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Atrioventricular Valve Morphogenesis Endoderm Development Nitrogen Compound Metabolic Process Formation Of Primary Germ Layer Cell Differentiation Atrioventricular Valve Development Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transcription From RNA Polymerase II Promoter Organ Development Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Embryo Development Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process SMAD Protein Complex Assembly Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Pattern Specification Process
Tagcloud ?		behnke biomicroscopic bucklers corneal dilated dystrophies dystrophy families fundus gcd1 gcd2 granular inheritance inspection korean l527r lattice lcd opacities ophthalmologic p527r p542r r124c r124h r555q refractive reis tgfbi thiel
Tagcloud (Difference) ?		behnke biomicroscopic bucklers corneal dilated dystrophies dystrophy families fundus gcd1 gcd2 granular inheritance inspection korean l527r lattice lcd opacities ophthalmologic p527r p542r r124c r124h r555q refractive reis tgfbi thiel
Tagcloud (Intersection) ?