TBCD

Name	tubulin folding cofactor D
Structure	No pdb structure
Interactors	14 interactors: ACD APP ARL2 COMMD4 DEXI MTDH MTNR1B POLR2I POT1 SMAD9 TBCE TERF1 TUBB XRCC6
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Microtubule Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Lateral Plasma Membrane Anchoring Junction
	Molecular Function	GTPase Activator Activity Protein Binding Beta-tubulin Binding Protein-folding Chaperone Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Microtubule Polymerization Adherens Junction Assembly Cell Morphogenesis Involved In Neuron Differentiation Bicellular Tight Junction Assembly
Pathways	Post-chaperonin tubulin folding pathway
GWAS	Blond vs. brown/black hair color ( 30531825 ) Bone mineral accretion in asthma (oral corticosteroid dose interaction) ( 26025128 ) Mean platelet volume ( 32888494 ) Moderate-to-late spontaneous preterm birth ( 31194736 ) Response to cognitive-behavioural therapy in anxiety and major depressive disorders ( 31123309 )
Entrez ID	6904
HPRD ID	05227
Ensembl ID	ENSG00000141556
Uniprot IDs	A0A804HI02 A0A804HIN6 A0A804HJ32 A0A804HJU6 A0A804HLI2 Q9BTW9
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Nuclear Telomere Cap Complex Telomeric DNA Binding Shelterin Complex Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Telomere Maintenance RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Telomere Organization Negative Regulation Of Telomere Maintenance Telomere Assembly Regulation Of Telomere Maintenance Via Telomerase Chromosome, Telomeric Region Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Double-stranded Telomeric DNA Binding Telomeric D-loop Disassembly Positive Regulation Of Telomere Maintenance G-rich Strand Telomeric DNA Binding Nuclear Envelope Lumen Telomeric Loop Disassembly Negative Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process DNA Biosynthetic Process Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Chromosome Organization Negative Regulation Of DNA Metabolic Process DNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Establishment Of Protein Localization Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleolus Positive Regulation Of Organelle Organization Maintenance Of Transcriptional Fidelity During Transcription Elongation By RNA Polymerase II Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly