TBCD and ARL2

Number of citations of the paper that reports this interaction (PMID 10831612)
43

Data Source:
HPRD (in vivo, in vitro)

		TBCD	ARL2
Gene Name		tubulin folding cofactor D	ADP-ribosylation factor-like 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Adherens Junction Tight Junction Lateral Plasma Membrane	Nucleus Mitochondrial Intermembrane Space Centrosome Lateral Plasma Membrane Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	GTPase Activator Activity Protein Binding Beta-tubulin Binding Chaperone Binding	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Protein Folding Post-chaperonin Tubulin Folding Pathway Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Microtubule Polymerization Adherens Junction Assembly Positive Regulation Of GTPase Activity Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Transmembrane Transport Tight Junction Assembly	Tubulin Complex Assembly Cell Cycle Small GTPase Mediated Signal Transduction Metabolic Process Positive Regulation Of Cell-substrate Adhesion Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Polymerization Negative Regulation Of GTPase Activity Centrosome Organization Maintenance Of Protein Location In Nucleus Tight Junction Assembly
Pathways		Protein folding Post-chaperonin tubulin folding pathway Orphan transporters	Protein folding Post-chaperonin tubulin folding pathway Orphan transporters
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ACD APP ARL2 DEXI POLR2I POT1 SMAD9 TBCE TERF1 TUBB XRCC6	5 interactors: ARL2BP PDE6D TBCD TBL1XR1 UNC119
Entrez ID		6904	402
HPRD ID		05227	11869
Ensembl ID		ENSG00000141556	ENSG00000213465
Uniprot IDs		J3KR97 Q9BTW9	B4DGG0 P36404 Q53YD8
PDB IDs			3DOE 3DOF
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Telomere Assembly Telomere Capping Positive Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cellular Biosynthetic Process Regulation Of DNA Replication Positive Regulation Of DNA Biosynthetic Process DNA Metabolic Process RNA-dependent DNA Replication Cellular Component Assembly Negative Regulation Of DNA Biosynthetic Process Organelle Organization Regulation Of Microtubule Polymerization Regulation Of Chromosome Organization Telomere Maintenance Via Telomere Lengthening Homeostatic Process Microtubule-based Process Negative Regulation Of Catalytic Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Replication Regulation Of Organelle Organization Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Maintenance Of Transcriptional Fidelity During DNA-templated Transcription Elongation From RNA Polymerase II Promoter DNA Duplex Unwinding Response To Stimulus DNA Geometric Change Positive Regulation Of Organelle Organization Chromosome Organization Nucleobase-containing Compound Metabolic Process Microtubule Cytoskeleton Organization Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process	Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Catalytic Activity Visual Perception Sensory Perception Of Light Stimulus Cytokinesis, Completion Of Separation Regulation Of Peptidyl-tyrosine Phosphorylation Post-chaperonin Tubulin Folding Pathway Regulation Of Caveolin-mediated Endocytosis Mitotic Cytokinetic Process Positive Regulation Of Metabolic Process Regulation Of Clathrin-mediated Endocytosis Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Microtubule Polymerization Regulation Of Metabolic Process Maintenance Of Protein Location In Nucleus Cell Separation After Cytokinesis Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Transport Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Microtubule Polymerization Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Protein Tyrosine Kinase Activity
Tagcloud ?		behnke biomicroscopic bucklers corneal dilated dystrophies dystrophy families fundus gcd1 gcd2 granular inheritance inspection korean l527r lattice lcd opacities ophthalmologic p527r p542r r124c r124h r555q refractive reis tgfbi thiel	attributed automata charged continuously diffusion electrostatic endomembranes endosome enrichment explains fitting geometries kinetic kras mislocalized pdedelta perinuclear phospholipids pm posttranslational prenylation proto realistic recycling relies restores sequestered unloaded vesicular
Tagcloud (Difference) ?		behnke biomicroscopic bucklers corneal dilated dystrophies dystrophy families fundus gcd1 gcd2 granular inheritance inspection korean l527r lattice lcd opacities ophthalmologic p527r p542r r124c r124h r555q refractive reis tgfbi thiel	attributed automata charged continuously diffusion electrostatic endomembranes endosome enrichment explains fitting geometries kinetic kras mislocalized pdedelta perinuclear phospholipids pm posttranslational prenylation proto realistic recycling relies restores sequestered unloaded vesicular
Tagcloud (Intersection) ?