MAP1A and ACTA1

Number of citations of the paper that reports this interaction (PMID 7820861)
6

Data Source:
HPRD (in vitro)

		MAP1A	ACTA1
Gene Name		microtubule-associated protein 1A	actin, alpha 1, skeletal muscle
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Microtubule Microtubule Associated Complex	Stress Fiber Extracellular Space Cytosol Striated Muscle Thin Filament Actin Filament Actin Cytoskeleton Sarcomere Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Structural Molecule Activity Protein Binding Microtubule Binding	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Myosin Binding ADP Binding
	Biological Process	Microtubule Cytoskeleton Organization Sensory Perception Of Sound	Muscle Contraction Response To Mechanical Stimulus Response To Extracellular Stimulus Response To Lithium Ion Cell Growth Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Fiber Adaptation Response To Steroid Hormone Skeletal Muscle Fiber Development
Pathways			Striated Muscle Contraction
Drugs		Estramustine
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 RAPGEF3 RAPGEF4 SPP1 TUBA4A TUBB UPF2	107 interactors: ABL1 ABRA ACTR10 ACTR1B ADSS AFAP1 AIF1 AJUBA AMOT CCIN CCT2 CCT4 CCT5 CFL1 CLIC5 CNN1 CORO2B COTL1 CTNND1 CTTN CYFIP1 CYTH1 DHX9 DLG1 DMD DNASE1 DNMBP DTNA EGFR EPB41 EPB41L2 EPS8 FGD4 FHOD1 FSCN1 GAS2 GAS7 GC GSN HCLS1 HDAC4 HIP1R HTRA2 IQGAP1 ITGA2 ITPKA KIF23 KLHL20 LASP1 MACF1 MAP1A MIB2 MINPP1 MYL1 MYLK MYO10 MYO6 MYO7A MYO9B NEXN NR3C2 NRAP PAK1 PARVA PCYT1B PFDN1 PFN1 PHACTR1 PLD1 PPP1R9B PRKCA PRKCD PRKCE RAC1 RPS6KB1 S100A1 S100A4 SCIN SMTN SNCA SORBS1 SPRR1A SPTA1 SPTAN1 SPTBN2 TAGLN TJP1 TLN1 TMSB4X TMSB4Y TNNI1 TNNI3 TNNI3K TP53 TPM2 TPM3 TRIM55 TRIM63 TTN USP25 USP6NL UTRN VASP VAV1 VCL VIL1 XIRP1
Entrez ID		4130	58
HPRD ID		02549	00030
Ensembl ID		ENSG00000166963	ENSG00000143632
Uniprot IDs		E9PGC8 P78559 Q504X9	P68133 Q5T8M7
PDB IDs			1T44
Enriched GO Terms of Interacting Partners?		Movement Of Cell Or Subcellular Component Cellular Localization Receptor Localization To Synapse Response To External Stimulus Cytoskeleton Organization Axonogenesis Axon Development Protein Localization To Synapse Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Platelet Activation Cell-cell Signaling Developmental Process Axon Guidance Neuron Projection Morphogenesis Muscle Contraction Blood Coagulation Hemostasis Cell Morphogenesis Involved In Differentiation Muscle System Process Establishment Of Localization In Cell Generation Of Neurons Neuron Projection Development Response To Stimulus Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Locomotion Multicellular Organismal Development Regulation Of Body Fluid Levels Cell Differentiation Synaptic Transmission Wound Healing System Development Nervous System Development Receptor Clustering Transport Neuron Development Cell Development Smooth Muscle Contraction Nucleotide Phosphorylation Establishment Or Maintenance Of Cell Polarity Cell Activation MRNA Export From Nucleus Cytoplasmic Transport Cellular Metal Ion Homeostasis Response To Wounding Cell Morphogenesis Organelle Organization Intracellular Transport	Actin Filament-based Process Actin Cytoskeleton Organization Cytoskeleton Organization Actin Filament Organization Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Movement Of Cell Or Subcellular Component Regulation Of Actin Filament-based Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cellular Component Organization Regulation Of Actin Filament Polymerization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Actin Filament-based Movement Muscle Contraction Muscle System Process Cell Projection Organization Organelle Organization Negative Regulation Of Protein Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Cellular Component Assembly Developmental Process Anatomical Structure Morphogenesis Anatomical Structure Development Negative Regulation Of Protein Complex Assembly System Development Actin-mediated Cell Contraction Response To Wounding Locomotion Cell Development Response To External Stimulus Cell Differentiation Wound Healing Multicellular Organismal Development Cell Morphogenesis Negative Regulation Of Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Tissue Development Cell Projection Morphogenesis Chemotaxis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Neuron Development Actin Polymerization Or Depolymerization Blood Coagulation Hemostasis Cell Junction Assembly
Tagcloud ?		1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently	annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Difference) ?		1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently	annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Intersection) ?