MAP1A and SPP1

Number of citations of the paper that reports this interaction (PubMedID 22779921)
0

Data Source:
BioGRID (two hybrid)

		MAP1A	SPP1
Description		microtubule associated protein 1A	secreted phosphoprotein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Axon Dendrite Neuron Projection Neuronal Cell Body Axon Initial Segment Dendritic Shaft Dendritic Branch Synapse Primary Dendrite Dendritic Microtubule Axon Cytoplasm	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Vesicle Cell Projection Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Microtubule Binding Cytoskeletal Anchor Activity Tubulin Binding Tau Protein Binding	Cytokine Activity Integrin Binding Protein Binding Small Molecule Binding Extracellular Matrix Binding
	Biological Process	Microtubule Cytoskeleton Organization Axonogenesis Memory Associative Learning Dendrite Development Regulation Of Microtubule Depolymerization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Synaptic Plasticity Voluntary Musculoskeletal Movement Neuron Cellular Homeostasis Anterograde Axonal Protein Transport Retrograde Axonal Protein Transport Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Protein Localization Neuron Projection Maintenance Positive Regulation Of Protein Localization To Cell Surface	Ossification Osteoblast Differentiation Androgen Catabolic Process Cell Adhesion Signal Transduction Embryo Implantation Cell Differentiation Biomineral Tissue Development Response To Vitamin D Response To Macrophage Colony-stimulating Factor Positive Regulation Of Bone Resorption Positive Regulation Of DNA-templated Transcription Decidualization Response To Steroid Hormone Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Cellular Response To Testosterone Stimulus Response To 2,3,7,8-tetrachlorodibenzodioxine Positive Regulation Of Estradiol Secretion
Pathways			Degradation of the extracellular matrix Signaling by PDGF Integrin cell surface interactions Integrin cell surface interactions Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RUNX3 Regulates Immune Response and Cell Migration Post-translational protein phosphorylation Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
Drugs		Estramustine
Diseases
GWAS		Hemoglobin levels ( 32327693) Platelet count ( 27863252) Plateletcrit ( 27863252) Triglyceride levels x fish oil supplementation interaction (2df) ( 33760818) Triglycerides ( 24507774 30275531)	Blood protein levels ( 30072576) Dental caries ( 23064961) Gout ( 33832965) Urate levels ( 31578528)
Interacting Genes		28 interacting genes: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 CSNK2A1 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 OGT PRKAR1A RAPGEF3 RAPGEF4 RHOB SFN SPP1 TUBA4A TUBB UPF2 WEE2-AS1	97 interacting genes: ABCF3 ACP5 AFF4 AMOTL2 APOA1 ATP2A2 ATP5PB BAG6 BRD3 C1RL CACNG4 CALM1 CC2D1B CCR8 CD44 CEP162 CHD1 CIMIP5 CISD2 CMTM3 COMMD1 COPS5 CSNK2A1 CSNK2A2 CTNNBL1 CYB5R3 DCX DNAJB1 DNTTIP2 DRD2 DSEL EEF1A1 EIF3K EPAS1 ERBB2 F2 FTH1 GET3 GRIPAP1 HBA2 HMGN1 IGFBP5 ITGA5 ITGA9 ITGAV ITGB1 ITGB5 KCNIP1 LRRC4 MAP1A MAP1B MARCKS MEOX2 MMP3 MMP7 MPPED1 MRPL23 NACA NCKAP1 NCS1 NCSTN PDLIM7 PEMT PEPD PLD3 PRKACB PRKCA PRKG1 PTGER4 RANBP9 RAPGEF2 RBBP6 RIMS4 RPL13 RPL15 RPL5 RPS13 SEC24C SGTA SGTB SLC22A1 SLC39A6 SNAPIN SSB STAU1 STK39 TBC1D8 TMEM168 TMEM30A TPT1 TTC1 TUBB UBQLN4 USP42 USP8 ZNF638 ZNF804A
Entrez ID		4130	6696
HPRD ID		02549	01325
Ensembl ID		ENSG00000166963	ENSG00000118785
Uniprot IDs		E9PGC8 P78559 Q504X9	B7Z351 P10451 Q3LGB0
PDB IDs			3CXD 3DSF 9EOU
Enriched GO Terms of Interacting Partners?		Synapse Cytosol Glutamatergic Synapse Protein Kinase Binding Intracellular Protein Localization Organelle Organization Cellular Localization Regulation Of Transport Establishment Or Maintenance Of Cell Polarity CAMP Binding Neuromuscular Junction Regulation Of Cellular Component Organization Protein Localization To Cell Junction Intracellular Transport Intracellular Signal Transduction Establishment Of Localization In Cell Regulation Of Biological Quality Ionotropic Glutamate Receptor Binding Microtubule Muscle Contraction Cytoskeleton Organization Structural Constituent Of Cytoskeleton Regulation Of Secretion By Cell Presynapse Axon Regulation Of Cell Growth Non-canonical Inflammasome Complex Assembly Muscle System Process Regulation Of Secretion Intracellular Signaling Cassette Postsynaptic Density Nuclear Export Odontoblast Differentiation Nuclear RNA Export Factor Complex Small GTPase-mediated Signal Transduction Positive Regulation Of Protein Localization Receptor Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Urinary Bladder Smooth Muscle Contraction Receptor Clustering Establishment Or Maintenance Of Apical/basal Cell Polarity GMP Kinase Activity Smooth Muscle Contraction Regulation Of Synapse Organization Protein Localization To Synapse Positive Regulation Of Cell Growth Chemical Synaptic Transmission GDP Metabolic Process Positive Regulation Of Supramolecular Fiber Organization Juxtaparanode Region Of Axon	Cytosol Modulation Of Chemical Synaptic Transmission Wound Healing, Spreading Of Cells Regulation Of Ubiquitin-dependent Protein Catabolic Process Integrin Complex Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Biological Quality Microtubule Associated Complex Regulation Of Protein Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Lamellipodium Membrane Regulation Of Proteolysis Extracellular Exosome Integrin-mediated Signaling Pathway Cell-matrix Adhesion Negative Regulation Of Proteolysis Negative Regulation Of Proteasomal Protein Catabolic Process Integrin Alpha5-beta1 Complex Cell Adhesion Mediated By Integrin Integrin Alpha9-beta1 Complex Integrin Alphav-beta5 Complex Integrin Alphav-beta1 Complex Ribosomal Subunit TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Focal Adhesion Response To Stress Endodermal Cell Differentiation Developmental Process Negative Regulation Of Protein Catabolic Process Regulation Of System Process Protein Kinase CK2 Complex Alphav-beta3 Integrin-PKCalpha Complex Dendritic Microtubule Tail-anchored Membrane Protein Insertion Into ER Membrane Monoatomic Cation Transport Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Calcium Channel Regulator Activity Metal Ion Transport Regulation Of Proteasomal Protein Catabolic Process Regulation Of Synaptic Plasticity Regulation Of Protein Neddylation Biological_process Translation Dendritic Spine Cytosolic Ribosome Ruffle Membrane Cell-substrate Adhesion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?