MAP1A and MAP1LC3A

Number of citations of the paper that reports this interaction (PubMedID 7908909)
0

Data Source:
HPRD (in vitro, in vivo)

		MAP1A	MAP1LC3A
Description		microtubule associated protein 1A	microtubule associated protein 1 light chain 3 alpha
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Axon Dendrite Neuron Projection Neuronal Cell Body Axon Initial Segment Dendritic Shaft Dendritic Branch Synapse Primary Dendrite Dendritic Microtubule Axon Cytoplasm	Autophagosome Membrane Cytoplasm Late Endosome Autophagosome Cytosol Cytoskeleton Microtubule Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Autolysosome Synapse Glutamatergic Synapse
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Microtubule Binding Cytoskeletal Anchor Activity Tubulin Binding Tau Protein Binding	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Microtubule Cytoskeleton Organization Axonogenesis Memory Associative Learning Dendrite Development Regulation Of Microtubule Depolymerization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Synaptic Plasticity Voluntary Musculoskeletal Movement Neuron Cellular Homeostasis Anterograde Axonal Protein Transport Retrograde Axonal Protein Transport Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Protein Localization Neuron Projection Maintenance Positive Regulation Of Protein Localization To Cell Surface	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation JNK Cascade Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Response To Nutrient Levels Cellular Response To Amino Acid Starvation P38MAPK Cascade SMAD Protein Signal Transduction Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Cellular Response To Oxygen-glucose Deprivation Autophagosome Maturation
Pathways			Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy
Drugs		Estramustine
Diseases
GWAS		Hemoglobin levels ( 32327693) Platelet count ( 27863252) Plateletcrit ( 27863252) Triglyceride levels x fish oil supplementation interaction (2df) ( 33760818) Triglycerides ( 24507774 30275531)	Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		28 interacting genes: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 CSNK2A1 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 OGT PRKAR1A RAPGEF3 RAPGEF4 RHOB SFN SPP1 TUBA4A TUBB UPF2 WEE2-AS1	100 interacting genes: ABTB3 AKAP13 AMBRA1 ANK2 ANK3 ANKRD62 AP5B1 APOBR APP APPL1 ARHGAP6 ATF7IP2 ATG13 ATG2A ATG4B ATG7 ATXN3 BCL9 BNIP3L BRD9 CAMSAP1 CARS2 CCPG1 CDC37 CSAG1 DPPA4 DVL2 EPHA7 FUNDC1 GPSM1 HTATSF1 IRGQ IRS4 KIF15 KXD1 LINC00696 LMNB1 MAP1A MAP1S MAVS MDM2 MEFV MREG MRTFA MTX1 MYBPC1 NBR1 NCOR1 NEDD4 NEDD4L NEK9 NEURL4 OPRM1 OPTN PCNT PHB1 PIAS4 PRPF40A RABGAP1 RABGAP1L RASAL3 RDH12 RELB RESF1 RETREG3 RIC1 RTKN RTN3 SEC62 SLA2 SP1 SP3 SRPK1 STBD1 STK10 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TMEM132C TNIP1 TP53INP1 TP53INP2 TRIM21 TRIM25 TRIM32 TTN TUBA4A VPS9D1 ZBTB48 ZKSCAN4 ZNF304
Entrez ID		4130	84557
HPRD ID		02549	03144
Ensembl ID		ENSG00000166963	ENSG00000101460
Uniprot IDs		E9PGC8 P78559 Q504X9	Q9H492
PDB IDs			3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR 6TBE 7R9W 7R9Z 7RA0 8T2L 8T35 8T36 8T4T
Enriched GO Terms of Interacting Partners?		Synapse Cytosol Glutamatergic Synapse Protein Kinase Binding Intracellular Protein Localization Organelle Organization Cellular Localization Regulation Of Transport Establishment Or Maintenance Of Cell Polarity CAMP Binding Neuromuscular Junction Regulation Of Cellular Component Organization Protein Localization To Cell Junction Intracellular Transport Intracellular Signal Transduction Establishment Of Localization In Cell Regulation Of Biological Quality Ionotropic Glutamate Receptor Binding Microtubule Muscle Contraction Cytoskeleton Organization Structural Constituent Of Cytoskeleton Regulation Of Secretion By Cell Presynapse Axon Regulation Of Cell Growth Non-canonical Inflammasome Complex Assembly Muscle System Process Regulation Of Secretion Intracellular Signaling Cassette Postsynaptic Density Nuclear Export Odontoblast Differentiation Nuclear RNA Export Factor Complex Small GTPase-mediated Signal Transduction Positive Regulation Of Protein Localization Receptor Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Urinary Bladder Smooth Muscle Contraction Receptor Clustering Establishment Or Maintenance Of Apical/basal Cell Polarity GMP Kinase Activity Smooth Muscle Contraction Regulation Of Synapse Organization Protein Localization To Synapse Positive Regulation Of Cell Growth Chemical Synaptic Transmission GDP Metabolic Process Positive Regulation Of Supramolecular Fiber Organization Juxtaparanode Region Of Axon	Autophagosome GTPase Activator Activity Regulation Of Cilium Assembly Autophagy Macroautophagy Positive Regulation Of Catabolic Process Positive Regulation Of Autophagy Regulation Of Organelle Assembly Autophagosome Assembly Regulation Of Cell Projection Organization Autophagosome Organization Regulation Of Cell Projection Assembly Cytoplasmic Vesicle Regulation Of Autophagy Regulation Of Plasma Membrane Bounded Cell Projection Organization Autophagy Of Mitochondrion Organelle Organization Cytosol Vacuole Organization Mitophagy Positive Regulation Of Macroautophagy Regulation Of Macroautophagy Regulation Of Cellular Component Organization Piecemeal Microautophagy Of The Nucleus Regulation Of Organelle Organization Microautophagy Nucleophagy Positive Regulation Of Metabolic Process Substrate Localization To Autophagosome M Band Cytoskeleton Organization Phagophore Assembly Site Vesicle-mediated Transport Transcription Repressor Complex Intracellular Protein Localization Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Microtubule Associated Complex Regulation Of Protein Localization Negative Regulation Of Viral Process Catabolic Process Protein Kinase Regulator Activity Suppression Of Viral Release By Host Regulation Of Viral Process Regulation Of GTPase Activity Cytoplasm Ubiquitin Protein Ligase Activity Positive Regulation Of Protein Catabolic Process Cytoskeletal Anchor Activity Protein-macromolecule Adaptor Activity
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