MAP1A and DLG1

Number of citations of the paper that reports this interaction (PMID 9786987)
32

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		MAP1A	DLG1
Gene Name		microtubule-associated protein 1A	discs, large homolog 1 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Microtubule Microtubule Associated Complex	Immunological Synapse Basal Lamina Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Microtubule Plasma Membrane Cell-cell Junction Tight Junction Ionotropic Glutamate Receptor Complex Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Intercalated Disc Basolateral Plasma Membrane Lateral Plasma Membrane Cell Junction Cell Projection Membrane Neuromuscular Junction Node Of Ranvier Myelin Sheath Abaxonal Region Sarcolemma Lateral Loop Membrane Raft Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome MPP7-DLG1-LIN7 Complex
	Molecular Function	Structural Molecule Activity Protein Binding Microtubule Binding	Guanylate Kinase Activity Phosphoprotein Phosphatase Activity Protein Binding Protein C-terminus Binding Cytoskeletal Protein Binding Potassium Channel Regulator Activity Protein Kinase Binding Phosphatase Binding Mitogen-activated Protein Kinase Kinase Binding Protein Complex Scaffold Ionotropic Glutamate Receptor Binding Ion Channel Binding L27 Domain Binding
	Biological Process	Microtubule Cytoskeleton Organization Sensory Perception Of Sound	Branching Involved In Ureteric Bud Morphogenesis Immunological Synapse Formation Endothelial Cell Proliferation Lens Development In Camera-type Eye T Cell Cytokine Production Actin Filament Organization Mitotic Cell Cycle Checkpoint Establishment Or Maintenance Of Cell Polarity Synaptic Transmission Nervous System Development Axon Guidance Positive Regulation Of Cell Proliferation Viral Process Dephosphorylation Single Organismal Cell-cell Adhesion Peristalsis Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Membrane Raft Organization Regulation Of Myelination Activation Of Protein Kinase Activity T Cell Activation Negative Regulation Of T Cell Proliferation Regulation Of Membrane Potential Amyloid Precursor Protein Metabolic Process Receptor Clustering Positive Regulation Of Potassium Ion Transport Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Mitotic Cell Cycle Nucleotide Phosphorylation Reproductive Structure Development Embryonic Skeletal System Morphogenesis Smooth Muscle Tissue Development Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Protein Kinase B Signaling Hard Palate Development Tight Junction Assembly Protein Localization To Plasma Membrane Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Receptor Localization To Synapse Regulation Of Sodium Ion Transmembrane Transport
Pathways			Axon guidance Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity L1CAM interactions NrCAM interactions Activation of Kainate Receptors upon glutamate binding Activation of Ca-permeable Kainate Receptor Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ionotropic activity of Kainate Receptors Transmission across Chemical Synapses
Drugs		Estramustine
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 RAPGEF3 RAPGEF4 SPP1 TUBA4A TUBB UPF2	72 interactors: ACTA1 ACTN2 ADAM17 ADRB1 AKAP5 ATP2B2 ATP2B4 BAI1 BCR BEGAIN CACNG2 CALM2 CAMK2A CASK CNKSR2 CRIPT CTNNA1 DLG2 DLG3 DLGAP1 DLGAP3 DLGAP4 EPB41 ERBB4 EZR FZD4 FZD7 GDA GLS2 GNG13 GPR124 GPR125 GRIA1 GRIK2 GRIN2A GRIN2B GUCY1A2 KCNA1 KCNA2 KCNA3 KCNA4 KCNA5 KCNAB1 KCNJ10 KCNJ12 KCNJ2 KCNJ4 KCNJ6 KHDRBS1 KIF13B KIF1B LCK LRP2 LRRC1 MAP1A MAPK12 MPP2 MRPS34 MYO6 PARK2 PAX6 PBK PTEN SCN4A SCN5A SEMA4C STX4 TANC1 TJAP1 UBE3A WAS WNT3A
Entrez ID		4130	1739
HPRD ID		02549	03007
Ensembl ID		ENSG00000166963	ENSG00000075711
Uniprot IDs		E9PGC8 P78559 Q504X9	B4DF78 Q12959
PDB IDs			1PDR 2M3M 2OQS 2X7Z 3LRA 3RL7 3RL8 3W9Y 4AMH 4G69
Enriched GO Terms of Interacting Partners?		Movement Of Cell Or Subcellular Component Cellular Localization Receptor Localization To Synapse Response To External Stimulus Cytoskeleton Organization Axonogenesis Axon Development Protein Localization To Synapse Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Platelet Activation Cell-cell Signaling Developmental Process Axon Guidance Neuron Projection Morphogenesis Muscle Contraction Blood Coagulation Hemostasis Cell Morphogenesis Involved In Differentiation Muscle System Process Establishment Of Localization In Cell Generation Of Neurons Neuron Projection Development Response To Stimulus Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Locomotion Multicellular Organismal Development Regulation Of Body Fluid Levels Cell Differentiation Synaptic Transmission Wound Healing System Development Nervous System Development Receptor Clustering Transport Neuron Development Cell Development Smooth Muscle Contraction Nucleotide Phosphorylation Establishment Or Maintenance Of Cell Polarity Cell Activation MRNA Export From Nucleus Cytoplasmic Transport Cellular Metal Ion Homeostasis Response To Wounding Cell Morphogenesis Organelle Organization Intracellular Transport	Synaptic Transmission Cell-cell Signaling Signaling Cell Communication Regulation Of Ion Transmembrane Transport Regulation Of Ion Transport Metal Ion Transport Regulation Of Membrane Potential Neurological System Process Regulation Of Signaling Cation Transport Ion Transport Potassium Ion Transmembrane Transport Potassium Ion Transport Regulation Of Synaptic Plasticity Nervous System Development Response To Wounding Cation Transmembrane Transport Transport Ion Transmembrane Transport Regulation Of Cellular Localization Regulation Of Phosphorus Metabolic Process Neuron-neuron Synaptic Transmission Regulation Of Synaptic Transmission Response To Abiotic Stimulus Membrane Depolarization Regulation Of Cellular Process Regulation Of Signal Transduction Action Potential Monovalent Inorganic Cation Transport Response To Stimulus Potassium Ion Import System Development Transmembrane Transport Behavior Cellular Process Transmission Of Nerve Impulse Wound Healing Cellular Response To Stimulus Neuronal Action Potential Positive Regulation Of Transport Regulation Of Heart Contraction Cellular Localization Anatomical Structure Development Membrane Hyperpolarization Protein Homooligomerization Regulation Of Cellular Component Movement Regulation Of Body Fluid Levels Central Nervous System Development Neuromuscular Process
Tagcloud ?		1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently	adjust axonal b3 conditional ddit4 dephosphorylates dephosphorylation hypermyelination modulator mtorc1 myelin myelination nerves neuregulin pip3 pns precedes provokes ptdins pten redd1 rtp801 sap97 scaffolding schwann sustained tensin thickness tightly
Tagcloud (Difference) ?		1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently	adjust axonal b3 conditional ddit4 dephosphorylates dephosphorylation hypermyelination modulator mtorc1 myelin myelination nerves neuregulin pip3 pns precedes provokes ptdins pten redd1 rtp801 sap97 scaffolding schwann sustained tensin thickness tightly
Tagcloud (Intersection) ?