DEPTOR and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		DEPTOR	FBXO25
Gene Name		DEP domain containing MTOR-interacting protein	F-box protein 25
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of TOR Signaling Intracellular Signal Transduction Negative Regulation Of Cell Size Regulation Of Extrinsic Apoptotic Signaling Pathway	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APP BTRC CCDC110 CHKA FBXO25 LNX1 TRAF1	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		64798	26260
HPRD ID		13137	16439
Ensembl ID		ENSG00000155792	ENSG00000147364
Uniprot IDs		Q8TB45	Q8TCJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?		construct cytoreductive cytotoxic downregulation inducible knockdown latter mimics mirna mirnas mm mtor myeloma p21 paralysis prevented raptor resulted ruled senescence sgk shrna silence silencing torc1 transfection unfolded upregulation xenograft
Tagcloud (Difference) ?		construct cytoreductive cytotoxic downregulation inducible knockdown latter mimics mirna mirnas mm mtor myeloma p21 paralysis prevented raptor resulted ruled senescence sgk shrna silence silencing torc1 transfection unfolded upregulation xenograft
Tagcloud (Intersection) ?