RPS10 and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		RPS10	FBXO25
Gene Name		ribosomal protein S10	F-box protein 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Poly(A) RNA Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Protein Ubiquitination
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APP DMPK DNMT3B DVL3 EED FBXO25 HAP1 HIP1 KAT7 PFN2 PTTG1 SYK TCF25 WIZ XRCC6	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		6204	26260
HPRD ID		04697	16439
Ensembl ID		ENSG00000124614	ENSG00000147364
Uniprot IDs		P46783	Q8TCJ0
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Gene Expression Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Chromosome Organization Organelle Organization Gene Expression Regulation Of Vesicle-mediated Transport Positive Regulation Of Organelle Organization Regulation Of Exocytosis Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Protein Modification Process Genetic Imprinting Regulation Of Cell Differentiation Transcription, DNA-templated Positive Regulation Of Histone Methylation RNA Metabolic Process Regulation Of Gene Expression, Epigenetic Regulation Of Catalytic Activity RNA Biosynthetic Process Positive Regulation Of Cell Cycle Process DNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Axon Cargo Transport Regulation Of Cellular Process Regulation Of Histone Methylation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Cell Cycle Regulation Of Cellular Component Organization Regulation Of Neurogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Platelet Degranulation Positive Regulation Of JUN Kinase Activity Positive Regulation Of Histone Modification	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?		26t 2a aberrations anemia blackfan cgh congenital copy dba deletions diamond fourfold haploinsufficiency heterozygous hyperactivation hypoproliferative korean malformations predisposition reductions rpl11 rpl35a rpl5 rps17 rps19 rps24 rps26 supports variations
Tagcloud (Difference) ?		26t 2a aberrations anemia blackfan cgh congenital copy dba deletions diamond fourfold haploinsufficiency heterozygous hyperactivation hypoproliferative korean malformations predisposition reductions rpl11 rpl35a rpl5 rps17 rps19 rps24 rps26 supports variations
Tagcloud (Intersection) ?