PRRG1 and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		PRRG1	FBXO25
Gene Name		proline rich Gla (G-carboxyglutamic acid) 1	F-box protein 25
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Integral Component Of Plasma Membrane	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	Calcium Ion Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process		Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: FBXO25 NEDD4 NEDD4L	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		5638	26260
HPRD ID		05113	16439
Ensembl ID		ENSG00000130962	ENSG00000147364
Uniprot IDs		O14668 Q8NEK6	Q8TCJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Sodium Ion Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Negative Regulation Of Ion Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Protein Polyubiquitination Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Protein Catabolic Process Regulation Of Membrane Potential Response To Metal Ion Regulation Of Caveolin-mediated Endocytosis Progesterone Receptor Signaling Pathway Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Transport Regulation Of Ion Transmembrane Transport Negative Regulation Of Protein Localization To Cell Surface Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Tight Junction Assembly Response To Inorganic Substance Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Targeting To Lysosome Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Sodium Ion Homeostasis Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Localization To Lysosome Protein Catabolic Process Regulation Of Ion Transport Ventricular Cardiac Muscle Cell Action Potential Regulation Of Protein Localization To Cell Surface	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?		abrogation apobec3c arrays arrests birc3 bolus cdkn1a cleaved cultures depleted fas fluorouracil fu hct116 intra jmjd2b lamp3 myo1e parp proficient smaller sulf2 tacstd2 tncrna tnfrsf10b tp53 transcript unable zfyve20
Tagcloud (Difference) ?		abrogation apobec3c arrays arrests birc3 bolus cdkn1a cleaved cultures depleted fas fluorouracil fu hct116 intra jmjd2b lamp3 myo1e parp proficient smaller sulf2 tacstd2 tncrna tnfrsf10b tp53 transcript unable zfyve20
Tagcloud (Intersection) ?